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Harnessing the potential of the human body's own immune system to attack malignant tumor cells has been the goal of many scientific investigators in recent years, with advances in cancer biology and immunology enabling cancer immunotherapy to become a reality. World-class bench and clinical researchers have joined forces to collaborate and review current developments and trends in cancer immunology for the purposes of this book, and the result is a promising review of contemporary clinical treatments. In each chapter the authors present the scientific basis behind such therapeutic approaches, including cancer vaccines with special focus on prostate cancer, melanoma and novel approaches utilizing both innate and adaptive immune responses.
The book Modeling in Membranes and Membrane-Based Processes is based on the idea of developing a reference which will cover most relevant and “state-of-the-art” approaches in membrane modeling. This book explores almost every major aspect of modeling and the techniques applied in membrane separation studies and applications. This includes first principle-based models, thermodynamics models, computational fluid dynamics simulations, molecular dynamics simulations, and artificial intelligence-based modeling for membrane separation processes. These models have been discussed in light of various applications ranging from desalination to gas separation. In addition, this breakthrough new volu...
An eye-opening exploration of membrane contactors from a group of industry leaders In Membrane Contactor Technology: Water Treatment, Food Processing, Gas Separation, and Carbon Capture, an expert team of researchers delivers an up-to-date and insightful explanation of membrane contactor technology, including transport phenomena, design aspects, and diverse process applications. The book also includes explorations of membrane synthesis, process, and module design, as well as rarely discussed process modeling and simulation techniques. The authors discuss the technical and economic aspects of this increasingly important technology and examine the geometry, flow, energy and mass transport, and...
Part I. Democratic peace, conflict prevention, and the United Nations. Part II. Secularization and democracy. Part III. National and regional experiences.
Making Home(s) in Displacement critically rethinks the relationship between home and displacement from a spatial, material, and architectural perspective. Recent scholarship in the social sciences has investigated how migrants and refugees create and reproduce home under new conditions, thereby unpacking the seemingly contradictory positions of making a home and overcoming its loss. Yet, making home(s) in displacement is also a spatial practice, one which intrinsically relates to the fabrication of the built environment worldwide. Conceptually the book is divided along four spatial sites, referred to as camp, shelter, city, and house, which are approached with a multitude of perspectives ran...
A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and structural basis of sodium channel behavior. Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into the structural basis of sodium channel function. This volume of the Handbook of Experimental Pharmacology will explore sodium channels from the perspectives of their biophysical behavior, their structure, the drugs and toxins with which they are known to interact, acquired and inherited diseases that affect sodium channels and the techniques with which their biophysical and structural properties are studied.
This volume of al-Ṭabarī's history deals with the traumatic breakup of the Muslim community following the assassination of the Caliph 'Uthman. It begins with the first seriously contested succession to the caliphate, that of ʿAlī, and proceeds inexorably through the rebellion of 'A'ishah, T'alhah, and al-Zubayr, to the Battle of the Camel, the first time Muslim army faced Muslim army. It thus deals with the very first violent response to the two central problems of Muslim history: who is the rightful leader, and which is the true community? It is a section with the weightiest implications for the Muslim interpretation of history, wide open to special pleading. There are the Shi'a who de...
"This volume covers the period from the end of the Neolithic era to the beginning of the seventh century of our era. This lengthy period includes the civilization of Ancient Egypt, the history of Nubia, Ethiopia, North Africa and the Sahara, as well as of the other regions of the continent and its islands."--Publisher's description
The present volume is a collection of excerpts from al-Ṭabarī's biographical work entitled The Supplement to the Supplemented (Dhayl al-mudhayyal). In the introduction to his History, al-Ṭabarī declared his intention to append to it a biographical work for the reader's convenience. Only a collection of excerpts has survived, however. It was first published as part of the Leiden edition of the History and is now presented as a volume in the Ṭabarī Translation Project. It brings together biographies of Companions, successors, and scholars of subsequent generations; many chapters are devoted to women related to the Prophet who played a role in the transmission of knowledge. The biograp...