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Pathophysiological Mechanisms of Sarcopenia in Aging and in Muscular Dystrophy: A Translational Approach
Loss of muscle mass and increased fibrosis characterize both sarcopenia of aging and muscular dystrophy. Research is increasingly showing that these two conditions also share several pathophysiological mechanisms, including mitochondrial dysfunction, increased apoptosis, abnormal modulation of autophagy, decline in satellite cells, increased generation of reactive oxygen species, and abnormal regulation of signaling and stress response pathways. This Research Topic will cover several mechanisms involved in aging and dystrophic sarcopenia and explore the therapeutic potential of various strategies for intervention.
Muscle-Tendon-Innervation Unit: Degeneration and Aging - Pathophysiological and Regeneration Mechanisms
Aging is characterized by progressive deterioration of walking ability. This function loss has multiple causes including central and peripheral nerve dysfunction, loss of muscle mass and strength, as well as joints and bone alterations. Muscle-tendon unit and its innervation has a pivotal role in motor function performance that can be disrupted by overuse degeneration and aging. Research has shown that overuse degeneration and aging also share some pathophysiological mechanisms including mitochondrial dysfunction, increased apoptosis, abnormal modulation of autophagy, decline in satellite cells, increased generation of reactive oxygen species, and modification of signalling and stress response pathways. This Research Topic is intended to bring together basic researchers and clinicians working in the area of neuroscience, aging, sarcopenia and orthopaedics in human and in animal models. The aim of this cross-fertilization is to accelerate our understanding of the mechanisms involved in aging and degeneration of the muscle-tendon unit and its innervation and to explore the therapeutic potential of pharmacological and physical therapy interventions.
Western European Liberation Theology
Catholic action : a twentieth-century social movement, 1920s--1930s -- Theology and philosophy in the age of fascism, communism, and World War -- The politics of left Catholicism in the 1940s -- The Mouvement populaire des familles -- A working-class apostolate beyond Catholic action : team building, base communities, and worker priests -- Conclusion.
Neuromuscular Disorders in Clinical Practice
Comprehensive, thoroughly updated, and expanded, Neuromuscular Disorders in Clinical Practice, Second Edition encompasses all disorders of the peripheral nervous system, covering all aspects of neuromuscular diseases from diagnosis to treatment. Mirroring the first book, this two-volume edition is divided into two parts. Part one discusses the approach to neuromuscular disorders, covering principles and basics, neuromuscular investigations, and assessment and treatment of neurological disorders. Part two then addresses the complete range of specific neuromuscular diseases: neuronopathies, peripheral neuropathies, neuromuscular junction disorders, muscle ion channel disorders, myopathies, and...
Egypt Today
None
The Moment of Liberation in Western Europe
An innovative perspective on the visions at stake for post-liberation Western Europe, this work highlights initiatives arising from resistance activists. The moment of liberation is seen as a crucial moment, when a new society became a possibility.
Making Women's Medicine Masculine
Using sources ranging from the famous 12th-century female practitioner, Trota of Salerno, through to the great tomes of Renaissance male physicians, this is a pioneering study challenging the common belief that, prior to the 18th century, men were never involved in any aspect of women's healthcare in Europe.
Back Injury Prevention Handbook
Back injuries can be controlled and prevented! They are not and should not be accepted as a cost of doing business! Written in plain language for the industrial professional, this book presents back injury prevention methods that have proven effective for cost containment. Such techniques include the 5-year back attack, the Olympic weight lifting model applied to the industrial setting. Training styles, and concepts for a proper educational format are also emphasized. The author draws on literature from around the world and his own experience of over 20 years of treating and preventing back pain and neck pain in presenting information in this book. Several case studies prove that back injuries can be prevented, which can save hundreds of thousands of dollars and countless hours of lost work. This book will prove essential for helping trainers, safety specialists, ergonomists, industrial hygienists, and other industry personnel to implement the best cure for back pain-prevention!
Muscle Disorders in Childhood
This reference focuses on the clinical assessment, diagnosis, management, and prognosis of all forms of muscle diseases that affect children. Includes a readable account of relevant genetics, biochemistry, and molecular biology, in addition to numerous case histories.
