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Chronic Myeloproliferative Disorders
With the new classification of chronic myeloproliferative disorders, and the rise of interest in molecularly targeted therapies, this timely text brings together international experts on the topic to discuss the current technologies and their implications for the treatment of patients. This title comprehensively covers chronic myeloid leukemia and Ph-negative chronic myeloproliferative disorders and is an essential resource for all practitioners in Hematologic Oncology.
Cytotoxicity
The book Cytotoxicity is aimed to be an essential reading to all medical students, biologists, biochemists and professionals involved in the field of toxicology. This book is a useful and ideal guide for novice researchers interested in learning research methods to study cytotoxic bioactive compounds. The parts of this book describe the replacement and different applications of the cytotoxic agents. All chapters are written by paramount experts in cytotoxicity research. This will hopefully stimulate more research initiatives, funding, and critical insight into the already increasing demand for cytotoxicity researches that have been evidenced worldwide.
Bio-Applications of Nanoparticles
This edited book highlights the central players in the Bionanotechnology field - which are the nanostructures and biomolecules. It provides broad examples of current developments in Bionanotechnology research and is an excellent introduction to the field. The book describes how nanostructures are synthesized and details the wide variety of nanostructures available for biological research and applications. Examples of the unique properties of nanostructures are provided along with the current applications of these nanostructures in biology and medicine. The final chapters of the book describe the toxicity of nanostructures.
Cystogenesis
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted calcium homeostasis and aberrant intracellular cyclic AMP (cAMP) accumulation. Increased cell proliferation with fluid secreti...
Concise Encyclopedia of Coding Theory
Most coding theory experts date the origin of the subject with the 1948 publication of A Mathematical Theory of Communication by Claude Shannon. Since then, coding theory has grown into a discipline with many practical applications (antennas, networks, memories), requiring various mathematical techniques, from commutative algebra, to semi-definite programming, to algebraic geometry. Most topics covered in the Concise Encyclopedia of Coding Theory are presented in short sections at an introductory level and progress from basic to advanced level, with definitions, examples, and many references. The book is divided into three parts: Part I fundamentals: cyclic codes, skew cyclic codes, quasi-cy...
Sojourners and Settlers
Among the many groups of Chinese who migrated from their ancestral homeland in the nineteenth century, none found a more favorable situation that those who came to Hawaii. Coming from South China, largely as laborers for sugar plantations and Chinese rice plantations but also as independent merchants and craftsmen, they arrived at a time when the tiny Polynesian kingdom was being drawn into an international economic, political, and cultural world. Sojourners and Settlers traces the waves of Chinese immigration, the plantation experience, and movement into urban occupations. Important for the migrants were their close ties with indigenous Hawaiians, hundreds establishing families with Hawaiia...
Physical Chemistry of Ionic Materials
Defects play an important role in determining the properties of solids. This book provides an introduction to chemical bond, phonons, and thermodynamics; treatment of point defect formation and reaction, equilibria, mechanisms, and kinetics; kinetics chapters on solid state processes; and electrochemical techniques and applications. * Offers a coherent description of fundamental defect chemistry and the most common applications. * Up-to-date trends and developments within this field. * Combines electrochemical concepts with aspects of semiconductor physics.
Evolutionary Optimization
The use of evolutionary computation techniques has grown considerably over the past several years. Over this time, the use and applications of these techniques have been further enhanced resulting in a set of computational intelligence (also known as modern heuristics) tools that are particularly adept for solving complex optimization problems. Moreover, they are characteristically more robust than traditional methods based on formal logics or mathematical programming for many real world OR/MS problems. Hence, evolutionary computation techniques have dealt with complex optimization problems better than traditional optimization techniques although they can be applied to easy and simple proble...
Harmony Search Algorithm
The Harmony Search Algorithm (HSA) is one of the most well-known techniques in the field of soft computing, an important paradigm in the science and engineering community. This volume, the proceedings of the 2nd International Conference on Harmony Search Algorithm 2015 (ICHSA 2015), brings together contributions describing the latest developments in the field of soft computing with a special focus on HSA techniques. It includes coverage of new methods that have potentially immense application in various fields. Contributed articles cover aspects of the following topics related to the Harmony Search Algorithm: analytical studies; improved, hybrid and multi-objective variants; parameter tuning...
