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This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.
Issues In Agroecology – Present Status and Future Prospectus not only reviews aspects of ecology, but the ecology of sustainable food production systems, and related societal and cultural values. To provide effective communication regarding status and advances in this field, this series connects with many disciplines such as sociology, anthropology, environmental sciences, ethics, agriculture, economics, ecology, rural development, sustainability, policy and education, and integrations of these general themes so as to provide integrated points of view that will help lead to a more sustainable construction of values than conventional economics alone. Such designs are inherently complex and dynamic, and go beyond the individual farm to include landscapes, communities, and biogeographic regions by emphasizing their unique agricultural and ecological values, and their biological, societal, and cultural components and processes.
This book provides a decentralized approach for the identification and control of robotics systems. It also presents recent research in decentralized neural control and includes applications to robotics. Decentralized control is free from difficulties due to complexity in design, debugging, data gathering and storage requirements, making it preferable for interconnected systems. Furthermore, as opposed to the centralized approach, it can be implemented with parallel processors. This approach deals with four decentralized control schemes, which are able to identify the robot dynamics. The training of each neural network is performed on-line using an extended Kalman filter (EKF). The first ind...
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The words of this Mexican American working-class hero brought to English-language readers for the first time.
The Congressional Record is the official record of the proceedings and debates of the United States Congress. It is published daily when Congress is in session. The Congressional Record began publication in 1873. Debates for sessions prior to 1873 are recorded in The Debates and Proceedings in the Congress of the United States (1789-1824), the Register of Debates in Congress (1824-1837), and the Congressional Globe (1833-1873)