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Logic and Programming
In contrast to the effortless ease with which human beings control their limbs, the design of controllers for robotic manipulator arms is a detailed, meticulous business. Motors controlling the arms need to be started and stopped at just the right moment so that the performance demanded by the user may be achieved at the end of a complicated manoeuvre. And yet, the same user wishes to express the task for the robot in the simplest possible terms without reference to the minute details of control sequences that his task demands. It is the design of such inter faces between man and machine that is the subject of trus volume. Parent and Laurgeau develop the subject in a direct and logical order...
The Mechanical Behavior of Salt X
Rock salt formations have long been recognized as a valuable resource - not only for salt mining but for construction of oil and gas storage caverns and for isolation of radioactive and other hazardous wastes. Current interest is fast expanding towards construction and re-use of solution-mined caverns for storage of renewable energy in the form of hydrogen, compressed air and other gases. Evaluating the long term performance and safety of such systems demands an understanding of the coupled mechanical behavior and transport properties of salt. This volume presents a collection of 60 research papers defining the state-of-the-art in the field. Topics range from fundamental work on deformation ...
Cellular Trafficking of Cell Stress Proteins in Health and Disease
Since the beginning of the 21st Century there has been a rapid increase in our understanding of the cellular trafficking mechanisms of molecular chaperones in eukaryotes and in prokaryotes. In the former, molecular chaperone trafficking can occur between the various cellular compartments, with concomitant movement of other proteins. Such events can also result in the release of molecular chaperones from cells. In bacteria, molecular chaperones are involved in the trafficking of other proteins and are themselves released into the external milieu. The increasing appreciation of the role of molecular chaperones and Protein-Folding Catalysts in the interplay between bacteria and the cells of their hosts is now an important area of research for understanding the mechanisms of infectious diseases. This volume brings together experts in the biochemistry, cellular biology, immunology and molecular biology of molecular chaperones and Protein-Folding Catalysts with a focus on the mechanisms of cellular trafficking of these proteins and the role of these variegated trafficking mechanisms in both human and animal health and disease.
Context-Aware Mobile and Ubiquitous Computing for Enhanced Usability: Adaptive Technologies and Applications
Provides research developments on mobile technologies and services. Explains how users of such applications access intelligent and adaptable information services, maximizing convenience and minimizing intrusion.
Molecular Chaperones and Cell Signalling
This book reviews understanding of the biological roles of extracellular molecular chaperones. It provides an overview of the structure and function of molecular chaperones, their role in the cellular response to stress and their disposition within the cell. It also questions the basic paradigm of molecular chaperone biology - that these proteins are first and foremost protein-folding molecules. Paradigms of protein secretion are reviewed and the evolving concept of proteins (such as molecular chaperones) as multi-functional molecules for which the term 'moonlighting proteins' has been introduced is discussed. The role of exogenous molecular chaperones as cell regulators is examined and the physiological and pathophysiological role that molecular chaperones play is described. In the final section, the potential therapeutic use of molecular chaperones is described and the final chapter asks the question - what does the future hold for the extracellular biology of molecular chaperones?
Sex and Gender Differences in Infection and Treatments for Infectious Diseases
This book provides an overview of the underlying sex-based and hormone-based differences in immunity, wound healing and pharmacokinetics, while also exploring how pregnancy affects immunity. The second part of the book shows, for the first time in a single volume, the growing number of infectious diseases for which sex and gender differences are noted, identifies common as well as distinct mechanisms mediating these differences and illustrates how responses to treatments might differ between the sexes. The awareness that males and females differ in their response to specific pathogens as well as to treatments for infectious diseases may yield sex-specific personalized treatments. This book will be of interest to basic scientists and clinicians in the fields of microbiology, immunology and pharmacology. Individuals working in academia, government and industry will also benefit from the information presented.
Vascular Biochemistry
This volume explores all aspects of vascular biochemistry and includes chapters that provide an understanding of vascular function with descriptions of tissue components present in the vascular wall as well as an exploration of the hemodynamic and metabolic activities associated with this function. In addition, some chapters explore the vasculature under conditions which mimic various disease states. The information provided in this volume will provide new insights into the mechanisms that control vascular function as well as therapies designed to treat vascular disease.
Component-Based Software Engineering
The 2010 Symposium on Component-Based Software Engineering (CBSE 2010) was the 13th in a series of successful events that have grown into the main forum for industrial and academic experts to discuss component technology. CBSE is concerned with the development of software-intensive systems from - dependently developed software-building blocks (components), the development of components, and system maintenance and improvement by means of com- nent replacement and customization. The aim of the conference is to promote a science and technology foundation for achieving predictable quality in software systems through the use of software component technology and its associated software engineering...
Intracellular Delivery II
This volume is a continuation of Volume 1 following the previously published Editorial. More emphasis is given to novel nanocarrier designs, their characterization and function, and applications for drug discovery and treatment. A number of chapters will deal with nanofibers as a new major application within the biomedical field with a very high success rate particularly in wound healing and diabetic foot and spine injuries. A major new subdivision will deal with mathematical methods for the assembly of nanocarriers both for simulation and function.
