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This book includes six chapters covering new vortex theories, vortex identification methods, and vortex simulation and applications. Vortices are ubiquitous in the universe and include tornados, hurricanes, airplane tip vortices, polar vortices, and even star vortices in the galaxy. Vortices are also building blocks, muscles, and sinews of turbulent flows. This book is useful for researchers in hydrodynamics, aerodynamics, thermodynamics, oceanography, meteorology, metallurgy, civil engineering, astronomy, biology, and more. It is also useful for research on the generation, sustenance, modeling, and controlling of turbulence.
Progress in basic and clinical immunology within the last two decades has provided profound insight into the immune system and its role in preventing endogenous and exogenous damage. In contrast, disbalances within this system can result in autoimmune disorders which may affect diverse organs and result in distinct clinical pictures. In many of these, however, the individual etiopathogenetic mechanisms are poorly understood and even more their clinical symptoms are hard to treat. The book offers insight into basic mechanisms of autoimmune disorders. It includes neurological, gastrointestinal, ophthalmological and skin diseases as well as current and future therapeutic options including immunomodulatory drugs and different vaccination strategies. By addressing diverse organ systems, both singular and shared features are elaborated. Thus an exchange of ideas is intended across research on single organ systems within a truly interdisciplinary setting.
This book contains the latest results on the plasma environment of Mars and its interaction with the solar wind. These results include mapping of the plasma environment with the instruments on Mars Express and Mars Global Surveyor, the latest numerical simulations, and theoretical studies. This comprehensive examination of the Mars environment also sets the stage for the interpretation of the Venus Express measurements.
2004 marks the 100th anniversary of the first description of the autoimmune disease paroxysmal cold hemoglobinuria, a rare hemolytic disorder, by Julius Donath and Karl Landsteiner. After a century of research, the list of autoimmune diseases has become impressive. With a prevalence of approximately 5% of the world-wide population, these chronic, debilitating conditions affect almost every major organ of the body and, for reasons that remain unclear, are much more prevalent in woman than in men. Despite our rapidly expanding knowledge of the cellular and molecular pathways that govern a normal immune response, deciphering the precise etiology of autoimmune diseases remains an important chall...
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Reactive Oxygen Species (ROS) are molecules generated naturally during cellular metabolic processes. They act as signaling agents that oversee specific biochemical pathways, playing a vital role in cell function and survival. However, an imbalance in ROS signaling or excessive ROS production can have harmful effects on the pathophysiology of diseases. ROS are crucial to cell signaling and are involved in various physiological processes. They modulate gene expression, regulate cell cycle progression, and influence immune responses. Although ROS are essential for normal cellular functions, an overabundance of these molecules can lead to oxidative stress, causing DNA damage, lipid peroxidation,...
Divided into two parts, the first four chapters of Comets and their Origin refer to comets and their formation in general, describing cometary missions, comet remote observations, astrochemistry, artificial comets, and the chirality phenomenon. The second part covers the cometary ROSETTA mission, its launch, journey, scientific objectives, and instrumentations, as well as the landing scenario on a cometary nucleus. Along the way, the author presents general questions concerning the origin of terrestrial water and the molecular beginnings of life on Earth, as well as how the instruments used on a space mission like ROSETTA can help answer them. The text concludes with a chapter on what scientists expect from the ROSETTA mission and how its data will influence our life on Earth. As a result, the author elucidates highly topical and fascinating knowledge to scientists and students of various scientific backgrounds, allowing them to work with ROSETTA's data.
An up-to-date progress report on the current status of solar-terrestrial relation studies with an emphasis on observations by the Russian Interball spacecraft and the Czech Magion subsatellites. Papers in the volume describe the various spacecraft in the International Solar-Terrestrial Program and the research questions that they are being used to address. The emphasis is on correlative studies employing multiple instruments and multiple spacecraft. The book begins with a description of each spacecraft active in 1998 and describes the roles they can play in correlative studies. This is followed by an up-to-date status report concerning ongoing studies of the solar wind, foreshock, bow shock, magnetopause, magnetotail, and ionosphere, with an emphasis on the observations made by the four Interball spacecraft. Readership: Researchers and graduate students of space physics and astrophysics.