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Minnesota Archive Editions uses digital technology to make long-unavailable books once again accessible to scholars, students, researchers, and general readers. Rich with historical and cultural value, these works are published unaltered from the original University of Minnesota Press editions. The books offered through Minnesota Archive Editions are produced in limited quantities according to customer demand and are available through select distribution partners.
Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery. However, new drugs have recently been developed particularly those targeting heat shock protein 90. As heat shock protein 90 functions to stabilize many of the oncogenes and growth promoting proteins in cancer cells, such drugs have broad specificity in many types of cancer cell and offer the possibility of evading the development of resistance through point mutation or use of compensatory pathways. Heat shock proteins have a further property that makes them tempting targets in cancer immunotherapy. These proteins have the ability to induce an inflammatory response when released in tumors and to carry tumor antigens to antigen presenting cells. They have thus become important components of anticancer vaccines. Overall, heat shock proteins are important new targets in molecular cancer therapy and can be approached in a number of contrasting approaches to therapy.
An intimate portrait of India’s child runaways, and the sociopolitical forces shaping their lives This intimate portrait examines the tracks, journeys, and experiences of child runaways in northern India. Jonah Steinberg situates children’s decisions to leave home and flee for the city in their larger cultural, social, and historical contexts, and considers histories of landlessness and debt servitude in narratives of child dislocation. The resulting work is an original perspective on the sociological trends in postcolonial India and a unique treatment of a population of individuals who live on the margin of society.
Turbulent times challenge democratic politics and governance in Western countries. Party systems, in many instances, have failed to produce solutions to vital policy problems, like immigration, state borders, welfare, or environmental issues. While subjective perceptions of macroeconomic outcomes are consistently related to political trust at the micro level, few studies have explored how individuals develop political engagement and identity. New insights are needed from studies focusing on how people become politically active and how political identities develop. Political Identity and Democratic Citizenship in Turbulent Times is a critical scholarly research publication that investigates, ...
This book analyzes climate policy integration processes by investigating cause-effect relations in cases of integrating climate policy in energy and land-use sectors of Indonesia and Mexico, taking a novel comparative case study approach. The book identifies root causes for integration outside of the public administration, discussing decisive factors in the political economy of the energy and land-use sectors. Showing how policy windows may open for the successful integration of climate policies nevertheless, the book addresses the need to identify and properly use these windows to establish the administrative and institutional arrangements for effective climate policy implementation. This b...
Climate change is an issue that has been generating a significant amount of discussion, research, and debate in recent years. Climate change continues to evolve at a rapid rate and continues to have a wide array of effects on everything from temperature to plant life. Beyond the negative environmental impacts, climate change is also proving to be a detriment to society with increasingly violent natural disasters and human health effects. It is essential to stay up to date on the latest in emerging research within this field as it continues to develop. The Research Anthology on Environmental and Societal Impacts of Climate Change discusses the varied effects of climate change throughout all a...
Internationally acclaimed Egyptian feminist writer Nawal El Saadawi's landmark novel Woman at Point Zero, published here with a new foreword. Firdaus is on death row. Her crime, the murder of a man. Born into poverty in a rural Egyptian village, her childhood dreams and ambitions had been met with neglect and abuse by the world and the men who rule it. Driven to sex work to support herself, she is faced with the moral outrage of society and the bitter knowledge that for a woman, true freedom comes only when all hope is abandoned. In Woman at Point Zero, Firdaus tells her unforgettable story. Woman at Point Zero is also available in audiobook format from audiobook retailers.
Mochtar Lubis was one of Indonesia’s best-known newspaper editors, authors and cultural figures, with a national, regional and international prominence that he retained from the early 1950s until his recent death in 2004. This book traces the major events in the life of Mochtar Lubis, which is also a prism through which much of Indonesia’s post-independence history can be interpreted. This book is also the story of Indonesia in the second half of the twentieth century, when the people of the archipelago became an independent nation, and when print media and the influential figures who controlled and produced newspapers, played a pivotal role in national political, educational and cultura...