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Alzheimer's Disease
Alzheimer’s disease is an increasingly common form of dementia and despite rising interest in discovery of novel treatments and investigation into aetiology, there are no currently approved treatments that directly tackle the causes of the condition. Due to its multifactorial pathogenesis, current treatments are directed against symptoms and even precise diagnosis remains difficult as the majority of cases are diagnosed symptomatically and usually confirmed only by autopsy. Alzheimer’s Disease: Recent Findings in Pathophysiology, Diagnostic and Therapeutic Modalities provides a comprehensive overview from aetiology and neurochemistry to diagnosis, evaluation and management of Alzheimer's disease, and latest therapeutic approaches. Intended to provide an introduction to all aspects of the disease and latest developments, this book is ideal for students, postgraduates and researchers in neurochemistry, neurological drug discovery and Alzheimer’s disease.
Advances in Biological Solid-State NMR
Advances in Biological NMR brings the reader up to date with chapters from international leaders of this growing field, covering the most recent developments in the methodology and applications of solid state NMR to studies of membrane interactions and molecular motions
Neurodegenerative Diseases
Neurodegenerative Diseases - Processes, Prevention, Protection and Monitoring focuses on biological mechanisms, prevention, neuroprotection and even monitoring of disease progression. This book emphasizes the general biological processes of neurodegeneration in different neurodegenerative diseases. Although the primary etiology for different neurodegenerative diseases is different, there is a high level of similarity in the disease processes. The first three sections introduce how toxic proteins, intracellular calcium and oxidative stress affect different biological signaling pathways or molecular machineries to inform neurons to undergo degeneration. A section discusses how neighboring glia...
Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic
Volume 19, entitled Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic of the series Metal Ions in Life Sciences centers on the role of metal ions in clinical medicine. Metal ions are tightly regulated in human health: while essential to life, they can be toxic as well. Following an introductory chapter briefly discussing several important metal-related drugs and diseases and a chapter about drug development, the focus is fi rst on iron: its essentiality for pathogens and humans as well as its toxicity. Chelation therapy is addressed in the context of thalassemia, its relationship to neurodegenerative diseases and also the risks connected with iron adminis...
Book of Roy
"From 1998 to 2005 Neil Drabble photographed an American teenager, Roy, as he grew from adolescence to early manhood. On one level this extensive body of work can be viewed as a fascinating document of an always-compelling transition. Closer scrutiny reveals further nuances; a collaboration, a partnership, a personal portrait and at the same time a universal picture of adolescence. Drabble chose not to depict significant events that might appear in a family album nor definitive moments associated with documentary photography. Instead, these photographs concentrate on the listless, off-scene periods, the 'in between moments' of everyday life. This focus on the marginal passages of disregarded time situates the viewer at the heart of adolescence, defined as the period between childhood and adulthood, suspended between longing (for the deferred promise of adulthood) and regret (for the loss of childhood as refuge). By photographing the same person repeatedly and intimately over their formative years, a sense of mirroring began to emerge, reawakening something of the artist's own adolescent self, blurring the line between portrait and self-portrait"--Provided by publisher.
Because You're Mine
Bestselling author/artist Nancy Tillman celebrates the lifelong bond between parent and child. Not just about newborns, Because You're Mine stands as a testament to a parent's protection and support of their child through all ages and stages. The clouds can blow, the wind can call, the snow can come, the rain can fall- but they’ll just have to wait in line . . . Because you’re mine. Because you’re mine. Like Love You Forever, this is sure to be an evergreen gift and a new classic.
Motion Sickness
For the narrator of "Motion Sickness," life is an unguided tour. Adrift in Europe, she improvises a life and a self. In London, she's befriended by an expatriate American Buddhist and her mysterious husband, or may or may not be stalking her. In Paris, she shacks up with Arlette, an art historian obsessed with Velazquez;s painting "Las Meinas." In Amsterdam, she teams up with a Belgian friend, who is studying prostitutes, and she tours Italy with deeply mismatched English brothers. And, as with an epic journey, the true trajectory is inwards, ever inwards, into her own dreams and desires...
On the Night You Were Born / La Noche En Que Tú Naciste (Bilingual - English/Spanish)
An English/Spanish bilingual edition of Nancy Tillman's heartwarming debut picture book for readers of all ages, On the Night You Were Born / La Noche En Que Tu Naciste. On the night you were born, the moon smiled with such wonder that the stars peeked in to see you and the night wind whispered. "Life will never be the same." On the night you were born, the whole world came alive with thanksgiving. The moon stayed up till morning. The geese flew home to celebrate. Polar bears danced. On the night you were born you brought wonder and magic to the world. Here is a book that celebrates you. It is meant to be carried wherever life takes you, over all the roads, through all the years.
What Would Lynne Tillman Do?
Features essays written by the author on different subjects, but often comes back to the questions what happens when men behave badly and when women behave too well.
