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This textbook, edited by three of the world's leading experts, profiles all aspects of this important field. Beginning with embryology and concluding with congenital heart defects in the newborn, it explains scientific and clinical principles with clarity and is illustrated with top quality scans. Fetal Cardiology is for all health care professionals performing targeted organ scans or with an interest in the fetal heart. Aimed especially at obstetricians, pediatric cardiologists and general cardiologists, this book includes chapters on treatment options-pharmacological or surgical interventions-available to affected fetuses, as well as all life-stages of heart disease, from embryology to adulthood. It also explores often-ignored areas such as the placenta, reproductive health of women with coronary heat disease, counseling of families affected with coronary heart disease, and future fetal treatments only now being developed. Fetal Cardiology will establish itself as the benchmark text.
This is the only in-depth, single author survey of heart development. It will provide a more systematic, up-to-date synthesis of the subject than any other volume, spanning the range from classical anatomical studies to recent findings in molecular biology. It also covers topics that are often omitted from discussions of heart development, such as myocardial function, cardiac innervation, and conduction development and clinical correlates will be discussed throughout. The book is beautifully illustrated by Karen Waldo, an artist who has collaborated with Dr. Kirby for many years.
The overall scope of this new series will be to evolve an understanding of the genetic basis of (1) how early mesoderm commits to cells of a heart lineage that progres sively and irreversibly assemble into a segmented, primary heart tube that can be remodeled into a four-chambered organ, and (2) how blood vessels are derived and assembled both in the heart and in the body. Our central aim is to establish a four-dimensional, spatiotemporal foundation for the heart and blood vessels that can be genetically dissected for function and mechanism. Since Robert DeHaan's seminal chapter "Morphogenesis of the Vertebrate Heart" published in Organogenesis (Holt Rinehart & Winston, NY) in 1965, there ha...
The material contained in this book was presented at the Boerhaave Course which was held in Leiden, The Netherlands, on May 2 and 3, 1977. It deals with three topics of considerably recent interest, not only to cardiologists and cardiovascular surgeons, but also to embryologists, anatomists and pathologists. Papers on the development and the normal anatomy of the conduction system include a discussion of the continuing controversy as to whether dis crete and anatomically distinct internodal pathways exist in the human heart. These are followed by descriptions of the abnormal anatomy and relation ships of the conduction system in certain complex cardiovascular anomalies. The rather startling ...
First multi-year cumulation covers six years: 1965-70.
La obra es un conjunto de los trabajos, ponencias y conclusiones del Congreso Internacional sobre Cardiología Pediátrica, celebrado en Madrid, con la asistencia de los líderes internacionales en la especialidad. Ha sido publicado en inglés para respetar la expresión de los 100 autores que participan en la misma.
Heart disease, despite recent improvements, continues to be the single most im portant cause of death and disability in the United States. It is estimated that the direct cost of medical care for cardiovascular disease is $6 billion dollars per year. Data compiled by the National Center for Health Statistics reveal a dramatic de cline in deaths from cardiovascular disease in the United States (greater than 20% since 1968). This phenomenon has been the subject of in-depth study. It is clear that the decline is real and not a statistical artifact. The decrease in mortality has been noted in all sections of the country, though the onset and rate of decline varies in different regions of the cou...
This book is an up-to-date summary of all aspects of aortic disease, written by international experts in their fields, covering diagnostic concepts of all aortic diseases, the most modern therapeutic approaches in various aortic syndromes, the pathogenic origin and the most recent molecular and cellular findings that have revolutionized our present knowledge of aortic diseases. The reader will come to understand the aorta as a functional organ with a complex regulatory system rather than just a major arterial vessel, and will have a better understanding of the prognostic impact of various aortic syndromes, and of the most recent therapeutic concepts for chronic as well as acute aortic pathol...
The pacemaking and conduction system (PCS) is vital for generating and synchronizing the heart beat. Dysfunction of this system can be a direct cause of cardiac conduction disturbance, arrhythmias and sudden cardiac death. A wealth of information has been collected over many years on the unique histological, morphological and phenotypic characteristics of specialized cardiac tissues. The cellular and molecular mechanisms that govern development of the PCS are now starting to be understood. This book draws together contributions from an international and interdisciplinary group of experts working on both basic and clinical aspects of cardiac development. It features reviews of the structure and function of the developing PCS, discussion of the molecular and cellular mechanisms regulating embryological development of this system and studies on the fundamental basis of PCS pathology. The book also considers how novel therapeutic interventions based on understanding of the developmental biology of cardiac pacemaking and conduction tissues might ultimately impact on clinical medicine.
This monograph had its genesis in a workshop on the specific conduction held in the spring of 1975. The meeting was organized to discuss present knowledge on structure and function of the cardiac specialized tissues with emphasis on their clinical implications. Since much new information was presented, the participants agreed to prepare manuscripts and make their material available for publication. This has resulted in a book in which the cardiac specialized tissues are discussed by different specialists: the electron-microscopist, anatomist, pathologist, physiologist, physicist and clinician. Apart from their interest in the cardiac conduction system the participants shared the opinion that...