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NEW YORK TIMES BESTSELLER • NAMED ONE OF THE BEST BOOKS OF THE YEAR BY NPR, BOOKPAGE, AND SHELF AWARENESS • “Paula McLain is considered the new star of historical fiction, and for good reason. Fans of The Paris Wife will be captivated by Circling the Sun, which . . . is both beautifully written and utterly engrossing.”—Ann Patchett, Country Living This powerful novel transports readers to the breathtaking world of Out of Africa—1920s Kenya—and reveals the extraordinary adventures of Beryl Markham, a woman before her time. Brought to Kenya from England by pioneering parents dreaming of a new life on an African farm, Beryl is raised unconventionally, developing a fierce will and ...
Reprint of the original, first published in 1872. The publishing house Anatiposi publishes historical books as reprints. Due to their age, these books may have missing pages or inferior quality. Our aim is to preserve these books and make them available to the public so that they do not get lost.
This first of two volumes provides a general overview of the genetics, structure, mechanism and regulation of the Ras superfamily proteins and describes in detail the signaling pathways and processes regulated by specific members of this family. The focus of this first volume is on the Rho and Ras subfamily of small G proteins. Renowned scientists provide insights into the biochemistry of the classical and non-classical small G-protein family members, their spatio-temporal regulation, their effectors and their roles in health and disease. Together with Volume 2, this book provides a comprehensive and state-of-the-art work on small G-proteins (GTPases). It is intended for graduates and professors in biochemistry and cell biology already working on small G-proteins (small GTPases), but also offers an extremely valuable resource for those readers who are new to the field.
La fonction du système cardiovasculaire est d acheminer oxygène et nutriments dans divers organes et de collectionner, en retour, le gaz carbonique. Pour assurer efficacement cette fonction de nutrition et d entretien, le système cardiovasculaire a besoin de maintenir l intégrité de sa structure anatomique pour pouvoir répondre aux différentes stimulations hormonales. Nous avons donc rassemblé, dans ce livre, les données scientifiques très bien connues pour rappeler la structure du système cardiovasculaire et surtout pour souligner les principes qui gouvernent la signalisation dans les cellules cardiovasculaires. Les mécanismes comparables décrits avec d autres types de cellules ont été aussi rapportés.