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Chemicals in the Environment and Brain Development: Importance of Neuroendocrinological Approaches
Mounting evidence shows that increasing numbers of children are being diagnosed with neurodevelopmental disorders, and it is clear that this increase cannot be explained by genetic background alone. A number of studies, including epidemiological studies, have found an association between in-utero and childhood exposure to certain chemicals, such as endocrine disruptors, psychoactive pharmaceuticals, volatile organic chemicals, persistent organic compounds and heavy metals, and children’s brain development. Yet, the mechanisms by which these chemicals impair brain development and function are not fully understood. In addition, little is known about how these chemicals enter and accumulate i...
Cerebral endothelial and glial cells are more than bricks in the Great Wall of the brain: insights into the way the blood-brain barrier actually works (Celebrating the centenary of Goldman’s experiments)
When Ehrlich discovered the first evidence of the blood-brain barrier in 1885, he probably did not perceive the Great Wall that remained hidden from consciousness inside the central nervous system. Ehrlich had observed that acidic vital dyes did not stain the brain if they were injected into the blood stream. A century ago (1913), Goldman showed that the injection of trypan blue in the cerebrospinal fluid stained only the brain, but not the other organs. For almost a century it was thought that the blood-brain barrier (BBB) consisted in a physical barrier, resulting from the restricted permeability of the cerebral endothelial cell layer, as they are joined by tight junctions. However, as sci...
Amazon Fruits: An Ethnobotanical Journey
This is the first comprehensive listing of Amazon fruits from an ethnobotanical perspective. This detailed book covers 50 botanical families, 207 species, in the Amazon including how the people of each region use them. It is lavishly illustrated with high-quality photographs taken by the author, an extensive list of references, and Dr. Smith’s latest, meticulous research. This book should be a foundational work for scholars working in the plant sciences, researchers in ethnobotanical studies, and general interest scholars seeking more detailed information on the latest research by a leading scientist in the Amazon.
Fazer e pensar a história medieval hoje
Fazer e pensar a História Medieval hoje. Guia de Estudo, Investigação e Docência tem como objectivo apresentar aos interessados em aprofundar os conhecimentos sobre a Idade Média, um conjunto de leituras e de temas actuais de investigação, e ainda propor estratégias de ensino e de aprendizagem sobre aquele período histórico. Após uma primeira parte dedicada a explicar os fundamentos da proposta, o livro aborda, sucessivamente, um conjunto de historiografias nacionais e uma selecção de temas relevantes da actual escrita da História pelos medievalistas. Practicing and reflecting medieval history, today. A guide for study, research and teaching aims to provide those interested in deepening their knowledge of the Middle Ages, a series of readings and current research topics, as well as to propose teaching strategies and learning guidlines about that historical period. After a first part dedicated to explaining the fundamentals of the proposal, the book addresses, in due turn, a set of national historiographies and a selection of relevant topics of the current writing of history by medievalists.
Eleisaun lideransa komunitariu, 09 outubro 2009
On process of conducting community leader elections in Timor-Leste in 2009; includes lists of elected candidates by district.
Ecology and Conservation of the Maned Wolf
Wolves are controversial figures worldwide and much effort has focused on how to conserve them while addressing public concerns. With its solitary habits and fruit-eating diet, the endangered maned wolf roams the South American grasslands and swamps, playing a vital part in maintaining biodiversity hotspots. Compared to the grey wolf, little is known about its relationship with local people and the environment and the reasons for its decline, making research about this unique species an urgent concern. Ecology and Conservation of the Maned Wolf: Multidisciplinary Perspectives gathers the work of leading researchers from diverse disciplines and countries, covering up-to-date research on the b...
Learning Styles and Strategies for Management Students
Today, globalization, advances in technology, greater access to information, and communication via social networks generate an explosion of knowledge and cause the working world to experience rapid change based on knowledge and continuous learning. The challenge for universities is to have a curriculum that prepares students for this digital world, but many characteristics of the school curriculum have been unchanged for decades. Consequently, student experiences can be very different from the experiences required by the labor market. In a learning environment, the desired results will not be achieved if several essential elements are not considered in the instructional teaching process, inc...
Natura Urbana
A study of urban nature that draws together different strands of urban ecology as well as insights derived from feminist, posthuman, and postcolonial thought. Postindustrial transitions and changing cultures of nature have produced an unprecedented degree of fascination with urban biodiversity. The “other nature” that flourishes in marginal urban spaces, at one remove from the controlled contours of metropolitan nature, is not the poor relation of rural flora and fauna. Indeed, these islands of biodiversity underline the porosity of the distinction between urban and rural. In Natura Urbana, Matthew Gandy explores urban nature as a multilayered material and symbolic entity, through the le...
