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Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America
Neurodegenerative diseases are the most frequent cause of dementia, representing a burden for public health systems (especially in middle and middle-high income countries). Although most research on this issue is concentrated in first-world centers, growing efforts in South America are affording important breakthroughs. This emerging agenda poses new challenges for the region but also new opportunities for the field. This book aims to integrate the community of experts across the globe and the region, and to establish new challenges and developments for future investigation. We present research focused on neurodegenerative research in South America. We introduce studies assessing the interpl...
What can we make of theories of embodiment and the role of the human mirror neuron system?
In recent years, work surrounding theories of embodiment and the role of the putative mirror neuron system (MNS) in humans has gained considerable attention. If humans have developed a network of neurons that fire in response to other beings’ actions, as has been shown in macaques, this system could have vast implications for all kinds of cognitive processes unique to humans, such as language, learning, empathy and communication in general. The goal of tapping into and understanding such a system is a fascinating yet challenging one. One form of embodiment -- embodied linguistics -- suggests that the way we process linguistic information is linked to our physical experience of the concept ...
Interactions between emotions and social context - Basic, clinical and non-human evidence
The emotions that we feel and also those that we perceive in others are crucial to the social functioning of both humans and non-human animals. Although the role of context has been extensively studied in basic sensory processing, its relevance for social cognition and emotional processing is little understood. In recent years, several lines of research at the behavioral and neural levels have highlighted the bidirectional interactions that take place between emotions and social context. Experienced emotions, even when incidental, bias decision-making. Remarkably, even basic emotions can be strongly influenced by situational contexts. In addition, both humans and non-human animals can use em...
Learned Brain Self-Regulation for Emotional Processing and Attentional Modulation: From Theory to Clinical Applications
Mounting evidence in the last years has demonstrated that self-regulation of brain activity can successfully be achieved by neurofeedback (NF). These methodologies have constituted themselves as new tools for cognitive neuroscience establishing causal links between voluntary brain activations and cognition and behavior, and as potential novel approaches for clinical applications in severe neuropsychiatric disorders (e.g. schizophrenia, depression, Parkinson´s disease, etc.). Current developments of brain imaging-based neurofeedback include the study of the behavioral modifications and neural reorganization produced by learned regulation of the activity of circumscribed brain regions and neu...
