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Genetic Disorders Among Arab Populations
Arab populations have their “own” genetic disorders, both universal and particular. Genetic diversity within these source populations, along with the fact that the rates of inbreeding are often high and family sizes are often large, constitute conditions that facilitate the emergence and detection of phenotypes explained notably by autosomal recessive inheritance; in which case, the use of homozygosity gene mapping can facilitate the discovery of the corresponding genes. The present book includes 5 parts dealing with various aspects that relate to the genetic structure of Arabs and minorities within the Arab world as well as genetic disorders prevalent in this part of the world. It inclu...
Objective Anaesthesia Review
The third edition of Objective Anaesthesia Review has been fully updated to help postgraduates in their exam preparation. Presented in an easy to follow, question and answer format, this textbook covers a range of topics in anaesthesia. Divided into two sections, the first part discusses numerous diseases and disorders, and the second describes anaesthesia equipment. Many chapters in this new edition have been revised and new chapters have been added including ‘Acute Postoperative Pain’ in the first section and ‘Videolaryngoscopes’ in the second section. Key points Fully updated, third edition helping anaesthesia trainees prepare for examinations Easy to follow, question and answer format, covering many clinical cases and anaesthesia equipment Includes new chapters and 265 images and illustrations Previous edition published in 2012
The Oxford Handbook of Disability History
The Oxford Handbook of Disability History features twenty-seven articles that span the diverse, global history of the disabled--from antiquity to today.
Disability in the Ottoman Arab World, 1500-1800
This book is the first on the history of both physical and mental disabilities in the Middle East and North Africa during Ottoman rule.
Congenital Anomalies of the Ear, Nose, and Throat
The modern assessment, understanding, management, and prevention of congenital anomalies of the ear, nose, and throat require a multi-disciplinary approach. This book provides a complete coverage of the subject in a precise manner, bridging the gaps between the disciplines of genetics, otolaryngology, plastic surgery, and pediatrics. It is divided into nine sections. The first includes general chapters on medical genetics and dysmorphology, physical measurement of the head and face, epidemiology, human teratogenic effects, and prenatal diagnosis. These are followed by sections on the ear, nose and sinuses, mouth, palate, pharynx, craniofacial region, neck and upper aerodigestive tract. In ea...
Transcription Factors and Human Disease
Several general principles have emerged from the study of human transcription factors. First, germline mutations in genes encoding transcription factors result in malformation syndromes in which the development of multiple body structures is affected. Second, somatic mutations involving many of the same genes contribute to tumorigenesis. Third, transcriptional regulatory mechanisms demonstrate remarkable evolutionary conservation. Fourth, prenatal development and postnatal physiology are unified by the demonstration that a single transription factor can control the proliferation of progenitor cells during development and the expression within the differentiated cells of gene products that pa...
Pharmacogenetics
Genes are important modifiers of human response to drugs, hormones, and toxins. Patients and healthy individuals alike display significant differences in response and suffer adverse effects as a result of exposure to many therapeutic agents as well as occupational chemicals. This introductory text brings together laboratory methods and epidemiologic studies for defining the role of heredity in human drug response. This book will benefit graduate students in pharmacology, genetics, epidemiology, nursing, and public health, and will serve as a handy reference for pharmacists, epidemiologists, and physicians responsible for the delivery and administration of drugs.
A Bibliography of Islamic Criminal Law, Supplement
The present work supplements the original volume of A Bibliography of Islamic Criminal Law, the most extensive bibliography on Islamic criminal law ever compiled. Drawing on a multitude of sources online and offline this bibliography covers in its thematic section not only the classical crime categories of ḥudūd, qiṣāṣ and taʿzīr but also a large number of newly emerging and related fields. In a second section, dedicated to countries, eras and institutions Olaf Köndgen comprehensively covers the historical and modern application of Islamic criminal law in all its forms. Unlocking the richness of this sub-field of Islamic law, also with the help of two detailed indices, this innovative reference work is highly relevant for all those researching Islamic law in general and the application of Islamic criminal law over time in particular.
Inborn Errors of Development
In this book, the clinical chapters are organized into sections by defined developmental pathways or gene families, and each section is preceded by a general overview. For each disorder the authors cover the disease-causing genes, the role of these genes in development as elucidated in model organisms, the human mutations that have been identified, and the developmental pathogenesis of the condition. Clinical descriptions, along with discussions of therapy and counseling, are provided. This book will be an invaluable resource for physicians, dentists, and other health professionals and for basic scientists interested in developmental processes and genetic perturbations that affect them.
