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Antibiotics
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Antineoplastic and Immunosuppressive Agents
Over the past two decades a number of attempts have been made, with varying degrees of success, to collect in a single treatise available information on the basic and applied pharmacology and biochemical mechanism of action of antineoplastic and immunosuppressive agents. The logarithmic growth of knowledge in this field has made it progressively more difficult to do justice to all aspects of this topic, and it is possible that the present handbook, more than four years in preparation, may be the last attempt to survey in a single volume the entire field of drugs employed in cancer chemotherapy and immunosuppression. Even in the present instance, it has proved necessary for practical reasons ...
Progress in Medicinal Chemistry
PROGRESS IN MEDICINAL CHEMISTRY 7.
General Register
Announcements for the following year included in some vols.
Immunotherapy for Gastrointestinal Cancer
This book is about the manipulation of the immune system as a therapeutic approach to gastrointestinal cancer and its clinical applications, exploring therapeutic approaches which might be taken under the broad banner of immunotherapy. Starting by introducing concepts of modern immunology, the clinical applications of immunotherapy are then discussed. The reader will learn about the three broad classes of immune therapeutic agents: cell-based treatment; antibody therapy; cytokine application and the key effector cells and mechanisms which might cause tumour rejection. The reverse side of this equation, the genetic and molecular mechanisms which the tumour can use to escape immune control and regulation, is also discussed. Through reviewing the most up-to-date evidence, this volume provides an overview of the important scientific lessons learned from past failure of immunotherapeutics in the clinic and highlights more positive recent data, coupled to practical guidelines for clinical usage. Written by a team of worldwide experts, this is an indispensable guide for medical oncologists, surgical oncologists, radiation therapists, pharmacists, oncology nurse specialists.
Progress in Nucleic Acid Research and Molecular Biology
Progress in Nucleic Acid Research and Molecular Biology
Mechanism of Action of Antimicrobial and Antitumor Agents
This volume is the third in the series devoted to Antibiotics initiated by Springer Verlag in 1967. The first two volumes were devoted to the Mode of Action of Antibiotics and Biogenesis, respectively and were received graciously. During the intervening years these two works have been used often by research workers and students alike and have been quoted extensively. Although a number of other excellent treatises on antibiotics have appeared, the Springer series has set a standard for thoroughness and quality that meets the need of the scientific community. It is against this background that the present Editors set about the preparation of a third volume in the Series on Antibiotics. Since t...
Applied Multivariate Research
Multivariate designs were once the province of the very few exalted researchers who understood the underlying advanced mathematics. Today, through the sophistication of statistical software packages such as SPSS, virtually all graduate students across the social and behavioural sciences are exposed to the complex multivariate statistical techniques without having to learn the mathematical computations needed to acquire the data output. These students - in psychology, education, political science, etc. - will never be statisticians and appropriately so, their preparation and coursework reflects less of an emphasis on the mathematical complexities of multivariate statistics and more on the ana...
Chemistry of Nucleosides and Nucleotides
This third of four volumes continues the work of its well-received predecessors by providing comprehensive articles on specific lines of research. All volumes are written with medicinal chemists, organic chemists, physical chemists, and biological chemists in mind. Additionally, with the spate of recent research on the anticancer, antiviral, and antiparasitic properties of nucleosides and nucleotides, the volumes will interest oncologists, virologists, and pharmacologists.
Candidate Character Traits in Presidential Elections
Voter perceptions of the personal traits of presidential candidates are widely regarded to be important influences on the vote. Media pundits frequently explain the outcome of presidential elections in terms of the personal appeal of the candidates. Despite the emphasis on presidential character traits in the media, the scholarly investigation in this area is limited. In this book, David Holian and Charles Prysby set out to examine the effect that trait perceptions have on the vote, how these perceptions are shaped by other attitudes and evaluations, and what types of voters are most likely to cast a ballot on the basis of the character traits of the presidential candidates. Using the Americ...
