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Retinal Dystrophies
Retinal dystrophies are the major causes of incurable blindness in the Western world. Our insight into their aetiology has improved remarkably over the past decade and a number of key genes have been identified. Together with a more detailed understanding of disease processes, this knowledge is stimulating new approaches to therapeutic strategies involving gene therapy, growth factors and retinal cell transplantation. Molecular genetic studies have provided detailed information on the pathogenesis of retinal dystrophies. An important proof of principle that gene therapy holds great promise for the treatment of these conditions was demonstrated in the rds mouse: introduction of a functional c...
Retinal Disorders: Genetic Approaches to Diagnosis and Treatment, Second Edition
The retina is a layer of neural tissue that lines the inner eye and captures visual stimuli. This volume provides an update on retinal diseases, describing the genetic and pathophysiological basis of the diseases and advances in strategies to treat them. Topics covered in this essential volume include: - Genetics and pathophysiology of inherited retinal degenerations - Gene therapies - Visual prosthesis - Cell-based therapies - Preparing clinical trials, and outcome measures
Glaucome primitif à angle ouvert
Le glaucome est une maladie dégénérative du nerf optique qui entraîne une perte progressive de la vision commençant tout d'abord en périphérie et progressant graduellement vers le centre. Cette maladie est souvent associée à une pression intra-oculaire (PIO) élevée qui comprime et endommage les fibres du nerf optique et de la rétine. Dans d'autres cas, malgré une PIO normale, une circulation sanguine inadéquate entraîne la mort (nécrose) des cellules du nerf optique et de la rétine. La perte de vision associée au glaucome est permanente et irréversible. Sans traitement, cette maladie peut mener jusqu'à la cécité. Le glaucome est une maladie fréquente puisqu'il atteint 2 % de la population totale en France. Ce sujet de santé publique fera l'objet du rapport annuel de la SFO en 2014. Le rapport abordera : – les bases fondamentales et cliniques ; – la prise en charge thérapeutique ; – les aspects socio-économiques et juridiques ; – le dépistage et les incidences en terme de santé publique.
The Retina
This book covers the entire spectrum of retinology from basic genetics to clinical assessment, from common diseases to rare syndromes, and from simple medical treatment to complex vitreoretinal surgical procedures. The reader will learn about the retina in its entirety, which is fundamental to ophthalmic expertise. To aid in self-assessment, the book includes multiple-choice questions in exam format, which include detailed answers and are supplemented with diagrams and photos (from the author’s personal library of patient photos). The book is intended for those sitting for the popular post-graduate degrees in ophthalmology in Europe (EBO), the traditional Royal College of Ophthalmology exams (RCO) and their Asian counterparts, including the ICO. It will also be of interest to qualified ophthalmic surgeons/ophthalmologists and can be used to self-assess readers’ current state of knowledge.
Handbook of Nutrition, Diet, and the Eye
The Handbook of Nutrition, Diet and the Eye is the first book to thoroughly address common features and etiological factors in how dietary and nutritional factors affect the eye. The ocular system is perhaps one of the least studied organs in diet and nutrition, yet the consequences of vision loss can be devastating. One of the biggest contributors to complete vision loss in the western hemisphere is diabetes, precipitated by metabolic syndrome. In some developing countries, micronutrient deficiencies are major contributory factors to impaired vision. However, there are a range of ocular defects that have either their origin in nutritional deficiencies or excess or have been shown to respond...
Principles and Practice of Ophthalmology E-Book
Inside the 3rd edition of this esteemed masterwork, hundreds of the most distinguished authorities from around the world provide today's best answers to every question that arises in your practice. They deliver in-depth guidance on new diagnostic approaches, operative technique, and treatment option, as well as cogent explanations of every new scientific concept and its clinical importance. With its new streamlined, more user-friendly, full-color format, this 3rd edition makes reference much faster, easier, and more versatile. More than ever, it's the source you need to efficiently and confidently overcome any clinical challenge you may face. Comprehensive, authoritative, and richly illustra...
Artificial Vision
This book presents and analyses the most recent research dedicated to restoring vision in individuals who are severely impaired or blind from retinal disease or injury. It is written by the leading groups worldwide who are at the forefront of developing artificial vision. The book begins by discussing the difficulties in comparing and interpreting functional results in the area of very low vision and the principal prospects and limitations of spatial resolution with artificial tools. Further on, chapters are included by researchers who stimulate the surface or the pigment epithelial side of the retina and by experts who work on stimulating the optic nerve, the lateral geniculate body and the superficial layers of the visual cortex. Artificial Vision: A Clinical Guide collates the most recent work of key artificial vision research groups to explain in a comparable and stringent order their varying approaches, the clinical or preclinical outcomes and their achievements during the last years. Senior ophthalmic fellows and academic practitioners will find this guide to be an indispensable resource for understanding the current status of artificial vision.
Man Versus Microbe: What Will It Take To Win?
The COVID-19 pandemic that swept the planet in the early 2020s killed more than six million, delivered unimaginable human suffering and $22 trillion in lost global growth. We weren't prepared and should have been.Unraveling the secrets of microbes, an invisible parallel universe of tiny life forms all around us, is central to managing the big twenty-first-century challenges of pandemics, bioterrorism, food security and climate change. Scientists, technologists, entrepreneurs and political leaders are racing to decode this biological realm with powerful new tools to extend human lifespans and make the world safer and more prosperous. Yet such technologies need to be handled with care. The pri...
Taurine 8
Taurine 8 represents the combined efforts of investigators on the roles of the amino acid taurine on human health and disease. The chapters covered in this book are directly derived from presentations of the contributors at the 18th International Taurine Meeting held in Marrakech, Morocco in April 2012. The purpose of this book is to disseminate current findings on taurine's contribution in several organ systems. This book covers the following topics: Taurine in the Nervous System, Taurine in the Immune System, Taurine and Diabetes, and Taurine and the Cardiovascular System. Dr. Abdeslem El Idrissi, College of Staten Island and Dr. William L’Amoreaux, College of Staten Island, were co-chai...
