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A fascinating collection of thirty compelling stories about events that shaped the Emerald City, It Happened in Seattle describes everything from the battle of Seattle in 1856 to the Nisqually earthquake of 2001.
Traces keep time and make the past visible. As such, they continue to be a fundamental resource for scientific knowledge production in modernity. While the art of trace reading is a millennia-old practice, tracings are specifically produced in the photographic archive or in the scientific laboratory. The material traces of the forms represent the objects and causes to which they owe their existence while making them invisible at the moment of their visualization. By looking at different techniques for the production of traces and their changes over two centuries, the contributions show the continuities they have, both in the laboratories and in large colliders of particle physics. This volume, inspired by Carlo Ginzburg’s early works, formulates a theory of traces for the 21st century.
This volume provides a timely and useful introduction to the theory and practical application of image analysis in histology. This powerful research technique can be used to detect not only stored products in a cell (immunocytochemistry) but the synthetic machinery and the genes that control it (in situ hybridisation), as well as the specific binding sites that act as receptors for a molecule following its release (in vitro autoradiography). The book provides a good introduction for beginners before looking in greater detail at more advanced material in selected areas. The volume highlights the importance of technique in gathering quantitative information. The book is divided into four sections: introductory material, image acquisition, image processing, and applications. The applications areas include quantitative immunochemistry, quantification of nerves and neurotransmitters and automated grain counting in in situ hybridisation histochemistry.
First multi-year cumulation covers six years: 1965-70.
Since the first edition of Light Microscopy in Biology: A Practical approach was published, techniques in modern light microscopy have improved considerably. This fully updated edition includes revised topics from the first edition as well as coverage of techniques and technologies that have been developed since it was published. As before, the book starts with an explanation of the basic techniques, and goes on to describe current methods in: chromosome microscopy, immunohistochemistry, fluorescence microscopy, image building and video microscopy. Totally new topics covered include: confocal microscopy, calcium and pH imaging, microinjection techniques and nanovid microscopy. There are also whole chapters now devoted to reflection contrast microscopy and histomorphometry. This new edition will be of great interest to postgraduate and postdoctoral researchers in biomedicine and cell biology - both those experienced with light microscopic techniques and newcomers to the field.
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