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The settlement of the Hebrides is usually considered in terms of the state formation agenda. Yet the area was subject to successive attempts at plantation, largely overlooked in historical narrative. Aonghas MacCoinnich’s study, Plantation and Civility, explores these plantations against the background of a Lowland-Highland cultural divide and competition over resources. The Macleod of Lewis clan, ‘uncivil’, Gaelic Highlanders, were dispossessed by the Lowland, ‘civil,’ Fife Adventurers, 1598-1609. Despite the collapse of this Lowland Plantation, however, the recourse to the Mackenzie clan, often thought a failure of policy, was instead a pragmatic response to an intractable problem. The Mackenzies also pursued the civility agenda treating with Dutch partners and fending off their English rivals in order to develop their plantation.
It is now 10 years since the first edition of YAC Protocols was published in 1996. YAC Protocols was first produced to address the huge demand within the research community for a lab-based text that described in detail the wide range of uses for large insert yeast artificial chromosome (YAC) DNA clones. In doing this, the original editor, David Markie, and the many different contri- tors who provided descriptions of the protocols they used and developed, did a magnificent job. Indeed many of the techniques described within the first e- tion require little change and have stood up admirably to the test of time. Since the first edition, the use of YACs has proved invaluable for addressing a wi...
'We are the Pilgrims, master; we shall go, Always a little further; it may be, Beyond that last blue mountain barred with snow.' If there was ever anyone who went a little further, a little beyond, it was Alastair MacKenzie. In a career spanning 30 years, MacKenzie served uniquely with the New Zealand Army in Vietnam, the British Parachute Regiment, the British Special Air Service (SAS), the South African Defence Force's famed ParaBats, the Sultan of Oman's Special Forces and a host of private security agencies and defence contractors. MacKenzie lived the soldier's life to the full as he journeyed 'the Golden Road to Samarkand'. This extraordinary new work from the author of Special Force: The Untold Story of 22nd Special Air Service Regiment (SAS) vividly documents the experience of infantry combat in Vietnam, life with the Paras, the tempo of selection for UK Special Forces, covert SAS operations in South Armagh and SAS Counter Terrorist training on the UK mainland, vehicle-mounted Pathfinder Brigade insertions into Angola and maritime counter-terrorism work in Oman.
In this book William Mackenzie records a world of local legend, folklore and superstition, and charts the changes he saw in his lifetime in agriculture, education, the Church and, of course, emigration. He recounts the history of the leading families of Skye and also the lives and experiences of the crofters, for whose rights he actively campaigned in the 1880s. Old Skye Tales is a unique and valuable record, written by a man of intelligence and sensitivity, whose life spanned both the traditional and the modern world. As well as containing a large amount of information of the geography of the island (particularly the north), there are also important sections on crofting, the Church, as well as local superstitions, sayings, second sight and even local characters of his time. An entertaining and witty book, Old Skye Tales is a marvellous resource for the historian, as well as a fascinating compendium for all those who love one of Scotland's most famous islands. It is one of the most important sources for the history of the island.
Leading clinicians and scientists in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The area of tolerance induction and reprogramming of the immune system is also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection.
Protein Design: Methods and Applications presents the most up-to-date protein design and engineering strategies so that readers can undertake their own projects with a maximum chance of success. The authors present integrated computational approaches that require various degrees of computational complexity, and the major accomplishments that have been achieved in the design and structural characterization of helical peptides and proteins.
Leading chemists and engineers concisely explain the principles behind microchip capillary electrophoresis and demonstrate its use in a variety of biochemical applications, ranging from the analysis of DNA, proteins, and peptides to single cell analysis and measuring the impact of surface modification on flow in microfluidic channels. Since surface chemistry must be carefully considered for optimal operation at this scale, the authors also discuss methods of both adsorbed and covalent surface modification for its control. Fabrication methods for producing microchips with glass, poly(dimethylsiloxane), and other polymers are also provided so that even novices can produce simple devices for standard separations. Microchip Capillary Electrophoresis: Methods and Protocols provides a practical starting point for either initiating research in the field of microchip capillary electrophoresis or understanding the full range of what can be done with existing systems.
For several decades, Arabidopsis thaliana has been the organism of choice in the laboratories of many plant geneticists, physiologists, developmental biologists, and biochemists around the world. During this time, a huge amount of knowledge has been acquired on the biology of this plant species, which has resulted in the development of molecular tools that account for much more efficient research. The significance that Arabidopsis would attain in biological research may have been difficult to foresee in the 1980s, when its use in the laboratory started. In the meantime, it has become the model plant organism, much the same way as Drosophila, Caenorhabditis, or mouse have for animal systems. ...
At first glance, the U.S. decision to escalate the war in Vietnam in the mid-1960s, China's position on North Korea's nuclear program in the late 1990s and early 2000s, and the EU resolution to lift what remained of the arms embargo against Libya in the mid-2000s would appear to share little in common. Yet each of these seemingly unconnected and far-reaching foreign policy decisions resulted at least in part from the exercise of a unique kind of coercion, one predicated on the intentional creation, manipulation, and exploitation of real or threatened mass population movements. In Weapons of Mass Migration, Kelly M. Greenhill offers the first systematic examination of this widely deployed but...