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The Knowledge Growth Regime
‘This important new book provides a penetrating, novel analysis of the key role played by knowledge when viewed through the lens of Schumpeterian economics. It is loaded with important insights that highlight the primacy of knowledge and innovation to unleash economic growth.’ —David B. Audretsch, Indiana University Bloomington, USA This book combines the tools elaborated by the economics of knowledge and the legacy of Joseph Schumpeter to explore the emergence of the new knowledge economy and the shift away from the manufacturing industries. Antonelli analyzes the characteristics of the innovation process as a creative response based upon the accumulation, generation and exploitation of knowledge. He highlights the new structure of advanced economies, where knowledge is at the same time the prime input and output. With special attention to the limits of the new knowledge growth regime, raised by the role of finance, income distribution and intellectual property rights, this Palgrave Pivot recommends appropriate economic policies based upon an Open Technology approach.
The Ophthalmoscope
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Handbook on the Economic Complexity of Technological Change
This comprehensive and innovative Handbook applies the tools of the economics of complexity to analyse the causes and effects of technological and structural change. It grafts the intuitions of the economics of complexity into the tradition of analysis based upon the Schumpeterian and Marshallian legacies. The Handbook elaborates the notion of innovation as an emerging property of the organized complexity of an economic system, and provides the basic tools to understand the recursive dynamics between the emergence of innovation and the unfolding of organized complexity. In so doing, it highlights the role of organizational thinking in explaining the introduction of innovations and the dynamics of structural change. With a new methodological approach to the economics of technological change, this wide-ranging volume will become the standard reference for postgraduates, academics and practitioners in the fields of evolutionary economics, complexity economics and the economics of innovation.
Robert Altman
The life and work of motion picture director Robert Altman (1925-2006) are interpreted from a variety of perspectives in this collection of essays. Actors, historians, film scholars, and cultural theorists reflect on Altman and his five-decade career and discuss the significance of music, history and genre in his films. Two actors who have appeared in some of the filmmaker's most important works are prominently represented, with a statement from Elliot Gould (MASH, The Long Goodbye, California Split) and an essay by Michael Murphy (McCabe and Mrs. Miller, Nashville, Tanner '88). The collection ends with an essay on the importance of death in the director's final productions The Company (2003) and Prairie Home Companion (2006) by noted Altman scholar Robert T. Self.
The Economics of Knowledge Generation and Distribution
Contemporary capitalistic systems have been undergoing profound transformations determined by the transition towards the so-called knowledge based economy, i.e. a competitive system based on the capabilities firms have to create, use and circulate knowledge. These transformations concern both the characteristics of productive and innovative processes, and the resources used in these activities. This book captures these changes, where traditional R&D investments undertaken internally by firms are increasingly and strategically complemented by external sources of innovation and new knowledge. Collaborations between firms, and between firms and other organizations, as well as the mobility of hu...
Deciphering the T Cell Response in SARS-CoV-2 Infection
COVID-19 is a recently emerged infectious disease caused by the novel coronavirus SARS-CoV-2. The immune system has a primary role in pathogen elimination and a rapid and effective response can limit disease severity. In this context, T cells play the major role in cell mediated adaptive immune response. The protective role of CD4+ and CD8+ T cells has been inferred from studies on patients who recovered from SARS and MERS and accumulating data are now showing their relevance in SARS-CoV-2 infection. Moreover, memory T cells induced by previous pathogens can shape the susceptibility to, and the clinical severity of other infections, but the complete picture has yet to be elucidated. If the virus is not rapidly eliminated, COVID-19 may progress towards a secondary inflammatory phase that is directly responsible for a worsening in clinical symptoms and immune system impairment. Besides marked lymphopenia, COVID-19 patients’ T cell compartment displays several alterations involving different subpopulations of T cells in terms of phenotype, metabolic profile and functionality.
Evolution of Genetic Mechanisms of Antibiotic Resistance
Since the first introduction of antibiotics into clinical practice, microbial drug resistance has emerged as a major obstacle in the treatment of infections. Recently, the combination of emergence of a complex variety of multidrug resistant strains and the dearth of newly discovered molecules to effectively target and eliminate these strains, has made antibiotic resistance one of the major public health problems of this century. Although different strategies can be adopted to contain the emergence and spread of antibiotic resistance, including (i) antimicrobial stewardship, (ii) infection control, and (iii) tighter control over the use of antibiotics in agriculture and breeding, a better und...
A Cinema of Loneliness
An updated and expanded version of this classic study of contemporary American film, the new edition of A Cinema of Loneliness reassesses the landscape of American cinema over the past decade, incorporating discussions of directors like Judd Apatow and David Fincher while offering assessments of the recent, and in some cases final, work from the filmmakers--Penn, Scorsese, Stone, Altman, Kubrick--at the book's core.
