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"This unique book is the only current publication that provides readers with a brief, yet concise, collection of the latest advances in chemical and biological agent detection and/or their surveillance. Nano and Microsensors for Chemical and Biological Terrorism Surveillance compiles and gives in-depth detail on several detection schemes so that the reader is provided with a general sense of these micro and nanoscale sensing systems and platforms." --Book Jacket.
This comprehensive overview of chemiluminescence and bioluminescence covers historical developments, fundamental principles, recent advances, instrumentation, and applications.
Light-emitting reactions occur in some living organisms, and are also now extensively exploited by industry and various branches of biomedical science. Luminescence from the natural world, particularly from marine organisms, is increasingly being harnessed by genetic and chemical manipulation to enhance the quality of human life. This volume contains cutting-edge contributions from most of the world's leading researchers in this field. It presents an up-to-date compilation of the range of biomedical, strategic and ecological applications of chemiluminescence and bioluminescence. It documents and highlights the rapid advance in knowledge concerning both the mechanisms and the uses of luminescence, and covers all the important developments of recent years.
The threat of biological and chemical terrorism has driven the demand for timely techniques that can quickly detect the agent or agents used in an attack. The detection and/or prevention of these potential security threats provide significant scientific and technical challenges due to the combination of possible agents and modes of delivery available. This book will present a thorough look at the importance and technological challenges of mass spectrometry (MS) for the detection & identification of biological and chemical threats. This new contribution’s general aims are to draw the attention of recognized practitioners, experts and graduate students trying to grasp the latest MS developments in the cutting-edge fields of MS-biodefense technologies for the rapid/early/specific sensitive threat detection of pathogens, viruses, explosives, mycotoxins, chemical agents, and biological markers of xenobiotic chemicals.
This volume details the theories, mechanisms, technologies and trends for solving qualitative and quantitative problems in diverse areas of analytical research - emphasizing physicochemical principles. It focuses on deriving simpler and more extensive chemiluminescence (CL) detectors reflecting miniaturization trends, including narrow-bone and capillary liquid chromatography versus high-performance liquid chromatography and miniaturized high-performance thin-layer chromatography. It also covers the sensitivity, selectivity, wide detection range and versatility of CL-based methodologies.
Since the publication of Bioluminescence and Chemiluminescence, Part B, genes have been cloned that encode luciferases from an array of bioluminescent organisms, novel applications of these genes have been developed, and much has been learned of the fundamental chemistry, biochemistry, structural biology, and biophysics of these intriguing enzymes. New strategies for application of chemiluminescence technology have been developed and refined, promising to further reduce the need to use radioisotopes in basic research and clinical laboratory settings. Methods for detection of low levels of light continue to push the limits of detection, allowing ready monitoring in real time of intricate subc...
This book describes the design and the use of bioluminescent biosensors. It introduces beginners and experienced researchers starting in the microbiological biosensor domain to the practical aspects of building a luminescent microbial biosensor. It is also a source of information about other applications that use microbial cells. Each chapter focus
The use of light-emitting proteins for the detection of biomolecules provides fast and sensitive methods which overcome the disadvantages of radioactive labels and the high cost of fluorescent dyes. This reference work summarizes modern advanced techniques and their applications and includes practical examples of assays based on photoproteins. The book presents contemporary key topics like luminescent marine organisms, DNA probes, reporter gene assays and photoproteins, ratiometric sensing, use of photoproteins for in vivo functional imaging and luminescent proteins in binding assays, to name just a few, and is complemented by recent advances in instrumentation. Includes an introductory chapter by 2008 Chemistry Nobel laureate Osamu Shimomura.
The most important processes on the Earth`s surface occur in the Ocean where materials and energy are primarily exchanged. In the case of marine chemistry different fields of chemistry from organic to inorganic as well as thermodynamics and biochemistry are involved. Analytical Chemistry is a very important tool for the quantification of biogeochemical processes by providing correct and even more sophisticated methodologies. These are often directly applied 'in situ', in order to detect trace and ultra-trace natural and anthropogenic substances. Kinetic and thermodynamic studies allow us to establish whether the process occurs. Once discovered it is then possible to build up general models for environmental systems. This book gathers many aspects with the aim of creating a general picture of the chemical processes occurring in the marine environment