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Clinical Andrology
A major new international reference work on andrology from the EAU Section of Andrological Urology - covering such issues as male infertility, erectile dysfunction, late-onset hypogonadism, and reproductive cancers - that engages with contemporary concern for evidence based practice, minimizing interventions, and promoting male reproductive health.
Clinical Andrology
A major new international reference work on andrology from the EAU Section of Andrological Urology covering such issues as male infertility, erectile dysfunction, late-onset hypogonadism, and reproductive cancers that engages with contemporary concern for evidence based practice, minimizing interventions, and promoting male reproductive heal
Sperm Chromatin
Sperm DNA damage is common and has been associated with reduced rates of conception, impaired embryonic development and increased risk of miscarriage. Although the exact causes of sperm DNA damage are unknown, it is clear that infertile men possess substantially higher levels of sperm DNA damage than do fertile men. Written by leading, internationally renowned clinicians and basic scientists with expertise in sperm DNA, Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction provides readers with a thoughtful and comprehensive review of the biological and clinical significance of sperm DNA damage. The work covers the fundamental principles of sperm...
A Clinician's Guide to Sperm DNA and Chromatin Damage
This comprehensive, up-to-date text, which brings together the key practical elements of the rapidly evolving field of sperm DNA and chromatin abnormalities, is divided thematically into five main sections. Part I discusses human sperm chromatin structure and nuclear architecture, while part II presents laboratory evaluation of sperm DNA damage, including SCSA, SCD, TUNEL and Comet assays, and cytochemical tests. Biological and clinical factors in the etiology of sperm DNA damage are discussed in part III, including oxidative stress, abortive apoptosis, cancer, and environmental and lifestyle factors. Part IV presents clinical studies on the utility of sperm DNA damage tests, both with natur...
Andrology for the Clinician
Andrology for the Clinician consists of two parts: In Part One, the busy clinician can easily find the problem-orientated information he or she needs on such issues as male factor fertility problems, male contraception, and male genital tract infection and tumours. Part Two contains in-depth subject-orientated information and adds important scientific background information to the recommendations received in Part One. Several leading experts have contributed to this work, which has been extensively subedited by world-renowned editors to ensure a well-structured didactic design and homogeneous content. This outstanding book is of great value for all Urologists, Andrologists, Dermatologists, Endocrinologists, Gynaecologists, Reproductive Biologists, GPs, Gerontologists, Psychologists, Psychiatrists, Paediatricians and anyone else interested in the problems of male sex and constitution.
Oxford Textbook of Endocrinology and Diabetes
Now in its second edition, the Oxford Textbook of Endocrinology and Diabetes is a fully comprehensive, evidence-based, and highly-valued reference work combining basic science with clinical guidance, and providing first rate advice on diagnosis and treatment.
Testis cancer: genes, environment, hormones
Testicular cancer (TC) is the most common cancer in males aged 20-40 years, with a worldwide incidence of 7.5 per 100,000, but the rates vary considerably between countries and ethnic groups and there is evidence also for an increasing incidence in last decades. About 95% of all TCs are represented by testicular germ cell tumors (TGCTs), which include seminoma and non-seminoma histological types. It is generally assumed that the development of TGCT is under endocrine control. In particular, unbalanced androgen/estrogen levels and/or activity are believed to represent the key events for TGCT development and progression. Furthermore, recent evidence has suggested genetic association of TGCT wi...
The Skeptical Environmentalist
The Skeptical Environmentalist challenges widely held beliefs that the environmental situation is getting worse and worse. The author, himself a former member of Greenpeace, is critical of the way in which many environmental organisations make selective and misleading use of the scientific evidence. Using the best available statistical information from internationally recognised research institutes, Bjørn Lomborg systematically examines a range of major environmental problems that feature prominently in headline news across the world. His arguments are presented in non-technical, accessible language and are carefully backed up by over 2500 footnotes allowing readers to check sources for themselves. Concluding that there are more reasons for optimism than pessimism, Bjørn Lomborg stresses the need for clear-headed prioritisation of resources to tackle real, not imagined problems. The Skeptical Environmentalist offers readers a non-partisan stocktaking exercise that serves as a useful corrective to the more alarmist accounts favoured by campaign groups and the media.
