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Merck
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Pages: 40. Chapters: Alendronic acid, ARIAD Pharmaceuticals, Christian R. H. Raetz, Dalotuzumab, Darmstadt, Ezetimibe, Ezetimibe/simvastatin, Gardasil, George W. Merck, Heinrich Emanuel Merck, Indinavir, Ivermectin, Kenneth Frazier, Laropiprant, Lloyd Huck, Matuzumab, Merck & Co., Merck headquarters, Merck Index, Merck KGaA, Merck Manual of Diagnosis and Therapy, Merck Serono, Merck Sharpe & Dohme Federal Credit Union, Montelukast, Moxifloxacin, P. Roy Vagelos, Peter S. Kim, Raltegravir, Richard Clark (pharmacologist), Rizatriptan, Rofecoxib, Schering-Plough, Sirna Therapeutics, Sucrets, The Merck Manuals, Zostavax.
Effect of Locally Delivered Alendronic Acid on Bone Formation Around Porous Titanium Implants
"The purpose of this study was to determine the effects of local delivery ofthe bisphosphonate alendronic acid (AA) on bone formation around, withinand on porous titanium implants. Cylindrical rods 9mm in diameter and90mm in length were coated with either 0.2mg or 1.0mg of AA prior tobilateral surgical implantation into the femoral intramedullary canals of 10experimental canines. Twelve weeks after surgery the femora wereharvested and scanned with micro computed tomography (microCT) prior toprocessing for undecalcified thin section histology and analysis withbackscattered scanning electron microscopy (BSEM). MicroCT analysisshowed that both levels of AA significantly enhanced peri-implant bo...
Review of the Medical Use of Alendronate (Fosamax, Binosto)
Alendronic acid (INN) or alendronate sodium, sold under the trade name Fosamax among others, is a bisphosphonate drug used for osteoporosis, osteogenesis imperfecta, and several other bone diseases. It is marketed alone as well as in combination with vitamin D. Merck's U.S. patent on alendronate expired in 2008 and the drug is now available as a generic. It is the most widely prescribed bisphosphonate medicine in the United States. Alendronate inhibits osteoclast-mediated bone-resorption. Like all bisphosphonates, it is chemically related to inorganic pyrophosphate, the endogenous regulator of bone turnover. But while pyrophosphate inhibits both osteoclastic bone resorption and the mineraliz...
Primerjava učinkovitosti alendronske kisline in raloksifina z metaanalizo
Osteoporoza je kronična progresivna skeletna bolezen, za katero je značilna zmanjšana kostna masa in mikroarhitekturne spremembe kostnega tkiva. To ima za posledico večjo krhkost kosti, ki vodijo do nastanka zlomov. Ti so najpogostejša in najbolj resna posledica osteoporoze, saj poškodba pogosto povzroči hude bolečine, trajno invalidnost in celo smrt bolnikov. Zaradi vedno večjega števila obolelih za osteoporozo, bi torej uspešno preprečevanje osteoporoze in njenih posledic pomembno pripomoglo k občutno bolj kvalitetnemu življenju starajočih se oseb, pa tudi k zmanjševanju invalidnosti in umrljivosti zaradi te bolezni.Na razpolago imamo več zdravil za preprečevanje in zdrav...
Pharmaceutical Formulations for Older Patients
Pharmaceutical formulation design affects patient acceptability/adherence and pharmacokinetics of the drug. This is particularly important for older patients because of the physiological changes due to ageing and clinical/social circumstances related to medicine taking. This book provides a comprehensive review in the design of formulations to meet the needs of older patients. An overview of the key clinical, social and pharmaceutical factors affecting medication optimization, safety and acceptability in older adults is included, followed by patient-centric considerations including regulatory requirements, dosage form design and human factor studies. Advanced pharmaceutical technologies are discussed for their potential use in older adults such as 3D printing, long-acting oral formulations and novel vaccine technologies. The unique focus of the book will be of interest to pharmaceutical scientists in both industry and academia in searching for better formulations for older patients.
Handbook of Drug Administration via Enteral Feeding Tubes, 3rd edition
With over 400 drug monographs, this book covers the technical, practical and legal aspects that you should consider before prescribing or administering drugs via enteral feeding tubes.
Bisphosphonates and Osteonecrosis of the Jaw, Volume 1218
"This volume presents manuscripts stemming from the conference entitled 'Bisphosphonates & Osteonecrosis of the Jaw,' held May 19, 2007 at the New York Academy of Sciences
