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Side Reactions in Peptide Synthesis
Side Reactions in Peptide Synthesis, based on the author's academic and industrial experience, and backed by a thorough review of the current literature, provides analysis of, and proposes solutions to, the most frequently encountered side reactions during peptide and peptidomimetic synthesis. This valuable handbook is ideal for research and process chemists working with peptide synthesis in diverse settings across academic, biotech, and pharmaceutical research and development. While peptide chemistry is increasingly prevalent, common side reactions and their causes are often poorly understood or anticipated, causing unnecessary waste of materials and delay. Each chapter discusses common sid...
From Inclusion to Engagement
From Inclusion to Engagement challenges the ideologically driven academic discourse that has come to dominate inclusive education by presenting research-based knowledge about what actually works. Presents an innovative approach rooted in a biopsychosocial theoretical perspective – an approach that is still relatively misunderstood within the educational sphere Offers insights based on an extensive review of contemporary international research in the field Avoids the biases of ideology in favour of science-based social and educational outcomes The first comprehensive account of evidence-based interventions for students with Social, Emotional and Behavioural Difficulties
Noradrenergic Signaling and Astroglia
Noradrenergic Signaling and Astroglia integrates what is known about the active role of astroglia in the locus coeruleus-noradrenergic system and outlines the most recent advances in the field. It discusses the molecular mechanisms underlying norepinephrine-induced receptor activation in astroglia, cellular metabolism and CNS energy provision, in vitro, ex vivo, and in vivo models, gliosignalling and neuronal activity, and astroglial networks, gap junctions, and morphological plasticity. The book also addresses the role of astroglial adrenergic receptor activation in memory formation, cognition, regulation of sleep homeostasis, and lastly in neurological disorders, including trauma (cellular...
Beyond Listening
From both an international perspective and through combining theory, practice and reflection, this book examines critically how listening to young children in early childhood services is understood and practiced.
The Learning Relationship
This book offers a psychoanalytic perspective on learning and teaching and on many of the issues which preoccupy those who work in educational the origins of learning in children’s early relationships and at factors which help and hinder the educational process in later childhood and adolescence. Amongst the topics addressed in the book are the significance of play and playfulness, the impact of change, separation, times of transition, bereavement, bullying and racism. The author has aimed to set well-established psychoanalytic ideas about lear of current educational practice and to look at the teacher’s experience alongside that of the students.
Arctic tourism in times of change: Seasonality
The seasonal nature of tourism is increasingly receiving the attention of various actors: tourism destination planners and economic development strategists at all levels, tour operators and the diverse businesses that significantly depend on tourism, and the host communities who negotiate tourism’s potential to have both positive and negative impacts. The research report at hand identifies and discusses four main perspectives on the issues of seasonal tourism in the Arctic: local community perspectives; employment and workforce issues; the Arctification of northern tourism; and global environmental change. These themes form the key issues around which the challenges and opportunities related to seasonality of tourism can be placed and worked with. Based on the discussion, the report outlines recommendations related to developing a thriving and sustainable tourism sector in Arctic Europe.
The Wrong Prince
Meet Geo and Dmitri, the Princes of Tybiria. Though Geo's the athlete, it's bookish Dmitri who gets the credit - and faces the consequences - for slaying a foreign prince. But whose arrow was it, really? Lucie Camerlane, a baron's daughter, is Prince Geo's secret mistress...until she learns of her disastrous betrothal to none other than his brother, the Crown Prince Dmitri! When Dmitri is abducted at his own engagement party, his star-crossed brother and fiancée must set aside their woes and differences to rescue him from the impenetrable Wintersea fortress. A precocious castle ward, a fascinating love-quadrangle, a plot to murder the king, and a hit-woman harlot complete this action-packed romantic comedy in another wickedly fast-paced fantasy adventure from C.K. Brooke, prolific fantasy author. FIVE STARS FROM READERS' FAVORITE BOOK REVIEWS & AWARD CONTEST * HONORABLE MENTION IN THE 2017 GLOBAL EBOOK AWARDS * A Favorite Read of 2016 - For the Love of Fictional Worlds Blog * Featured Favorite Fantasy of 2016 - Up 'Til Dawn Book Blog
Fairness and Futurity
Fairness and Futurity: Essays on Environmental Sustainability and Social Justice brings together leading international figures in political theory and sociology, as well as representatives from the political community, to consider the normative issues at stake in the relationship between environmental sustainability and social justice. It raises important questions and sets out to provide the answers. If future generations are owed justice, what should we bequeath them? Is `sustainability' an appropriate medium for environmentalists to express their demands? Is environmental protection compatible with intra-generational justice? Is environmental sustainability a luxury when social peace has broken down? These essays emerged from three intensive seminars that involved participants in constant re-evaluations of their work, and which bought three distinct groups—environmental theorists, `mainstream' political theorists, and policy community members—into fruitful contact. In particular, the attempt to involve `mainstream' theorists in environmental questions, and to encourage environmentalists to use intellectual resources of political theory, should be highlighted.
