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Novalis® Shaped Beam Radiosurgery has set new standards by delivering highly precise radiation treatments to tumors anywhere in the body through the use of a proprietary multileaf collimator. By shaping the radiation beam to the exact contours of the tumor or lesion, Novalis permits maximum dose delivery to the entire tumor while protecting healthy tissue; this makes it eminently suitable for the treatment of irregularly shaped tumors. This book provides a complete guide to radiosurgery treatments with Novalis. After a thorough discussion of the clinical and technical basis for Shaped Beam Radiosurgery, current clinical applications are considered in detail, including brain, body, skull base, and spinal tumors as well as arteriovenous malformations. Careful consideration is also given to future developments and applications, including new technologies that promise to offer even more accurate treatments. This state-of-the-art book will appeal to a wide audience of physicians and their multidisciplinary clinical and technical collaborators.
Nanoneuroscience, nanoneurosurgery, and nanobioelectronics have the potential to revolutionize medicine and improve the prevention, diagnosis, and treatment of neurological disorders over the next 10-20 years. The Textbook of Nanoneuroscience and Nanoneurosurgery presents a state-of-the-art review of the field, providing current information about n
Recent advances in pharmacology and brain stimulation have led to the development of novel treatments for psychiatric disorders. These new advances have led to the development of a new subspeciality, Interventional Psychiatry. Interventional Psychiatry: Road to Novel Therapeutics reviews all specialized treatments including device-based interventions such as electroconvulsive therapy (ECT), repetitive transcranial magnetic stimulation (rTMS), and deep brain stimulation (DBS). This book discusses the procedure-based pharmacologic interventions including ketamine infusion therapy and psychedelic therapies. Internationally contributed, each this book outlines the state of the field, as well as implications for training and the role of the interventional psychiatrist in treatment teams. - Introduces an innovative approach combining both well-established and innovative methodologies - Includes an in-depth description of putative mechanisms of action - Features clinician-friendly presentation of indications, contraindications, and techniques - Outlines guidelines to foster fellowships in Interventional Psychiatry
This issue of the Neurosurgery Clinics of North America devoted to Intracranial Stereotactic Radiosurgery is Guest Edited by Dr. Bruce Pollock of the Mayo Clinic in Rochester, Minnesota. Articles in this issue include: Concepts and Techniques of Intracranial Stereotactic Radiosurgery; Stereotactic Radiosurgery of Intracranial Meningiomas; Stereotactic Radiosurgery of Pituitary Adenomas; Stereotactic Radiosurgery of Vestibular Schwannomas; Stereotactic Radiosurgery of Non-Vestibular Schwannomas; Multi-session Radiosurgery of Benign Intracranial Tumors; Stereotactic Radiosurgery of Intracranial Gliomas; Stereotactic Radiosurgery of Brain Metastases; Stereotactic Radiosurgery of Chordomas, Chondrosarcomas, and Glomus Tumors; Stereotactic Radiosurgery of Intracranial Arteriovenous Malformations; Stereotactic Radiosurgery of Intracranial Dural Arteriovenous Fistulas; Stereotactic Radiosurgery of Intracranial Cavernous Malformations; Stereotactic Radiosurgery for Trigeminal Neuralgia; and Stereotactic Radiosurgery for Epilepsy and Functional Disorders.
This book is one-of-a-kind comprehensive Radiosurgery Case Review Atlas that includes not only cranial and spinal cases, but also structural and functional radiosurgery ones. It categorizes the various radiosurgery-treated pathologies, presenting illustrative case reviews for each category. Each case includes a clinical summary, a treatment protocol, a radiosurgery dosimetry summary, the pre-radiosurgery images and the serial, short-term and long-term, follow up images illustrating the clinical and radiologic outcomes of the radiosurgery treatment. Offering the readers a handy step-by-step practical guide to perform safe and effective radiosurgery treatment, this will be a useful toolkit for neurosurgeons, radiation neuro-oncologists and radiation physicists (Radiosurgeons) conducting radiosurgery programs or involved in radiosurgery training.
Edited by an expert multidisciplinary team, Neuromodulation in Psychiatry is the first reference guide to address both invasive and non-invasive neuromodulation strategies used in psychiatry. Covers basic principles, technical aspects, clinical applications and ethical considerations Presents up-to-date evidence in comprehensive summaries suitable for all levels of experience Each technique is clearly explained along with its implications for real-world clinical practice Allows psychiatrists to make informed decisions regarding neuromodulation for their patients
Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts to highlight the latest updates on various forms of management of high grade glioma. Some of the articles included in this issue focus on Extent of Resection for Glioblastoma; Role of adjuvant radiation therapy; Survival benefit of the Temozolomide protocol; Alternative chemotherapeutic agents; The role of avastin; Radiology; Pseuodprogression and Treatment effect; Pathology; Medical Management; Management of insular gliomas; Use of motor mapping; GBM treatment with clinical trials for surgical resection; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Future role of CED for GBM treatment; Application of a vault nanoparticle therapy for GBM therapy; Management of high grade gliomas in pediatric populations; Targeting Glioma Stem Like Cells with a focus on CD 133; and Potential Role for STAT3 inhibitors in glioblastoma.
Principles and Practice of Stereotactic Radiosurgery, Second Edition serves as the definitive reference textbook for SRS practitioners. It provides a theoretical basis for the use of therapeutic radiation including imaging techniques and radiobiology. The bulk of the textbook contains chapters that are comprehensive in scope on all diseases that are treated by SRS. Lastly, it addresses administrative and technical aspects of running an SRS unit. Each chapter provides an expansive treatment of the subject, with emphasis placed on the technical aspects of SRS so that practitioners in this field can use it as a daily reference. Written by noted experts in the field, Principles and Practice of Stereotactic Radiosurgery, Second Edition is the only reference needed for neurosurgeons, radiation oncologists and medical physicists at all levels of training and practice who are interested in SRS.
Effectively perform today’s most state-of-the-art neurosurgical procedures with Youmans Neurological Surgery, 6th Edition, edited by H. Richard Winn, MD. Still the cornerstone of unquestioned guidance on surgery of the nervous system, the new edition updates you on the most exciting developments in this ever-changing field. In print and online, it provides all the cutting-edge details you need to know about functional and restorative neurosurgery (FRN)/deep brain stimulation (DBS), stem cell biology, radiological and nuclear imaging, neuro-oncology, and much more. And with nearly 100 intraoperative videos online at www.expertconsult.com, as well as thousands of full-color illustrations, th...
Handbook of Radiosurgery in CNS Disease is a concise and practical manual offering radiation oncology, neurology, and neurosurgery residents, trainees, fellows, and clinicians up-to-date information on the role of radiosurgery within the overall context of CNS disease management. The emphasis is on decision making and the evaluation of radiosurgery as a viable option among the suite of potentially applicable treatments, including frame-based systems, non-invasive body immobilization, and image-guided targeting. The book examines radiosurgery as a treatment modality for various CNS pathologies, discussing relevant radiobiology, current technology, and the technical aspects of specific procedu...