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Autoimmune thyroid diseases (AITD) are T cell-mediated organ-specific autoimmune disorders resulting from an immune dysregulation leading to a thyroid immune attack (Antonelli and Benvenga). Graves’ disease and Hashimoto’s thyroiditis are the two main clinical presentations of AITD, and their clinical hallmarks are thyrotoxicosis and hypothyroidism, respectively. In many cases, AITD may be associated in the same patient with other organ-specific autoimmune attacks (such as in the case of type II autoimmune polyglandular syndrome, or type I diabetes, etc). Furthermore, AITD and thyroid function abnormalities have been frequently described in patients with systemic rheumatologic autoimmune...
The title of this issue of the Nexus Network Journal, "Architecture, Mathematics and Structure," is deliberately ambiguous. At first glance, it might seem to indicate the relationship between what buildings look like and how they stand up. This is indeed one aspect of what we are concerned with here. But on a deeper level, the fundamental concept of structure is what connects architecture to mathematics. Both architecture and mathematics are highly structured formal systems expressed through a symbolic language. For architecture, the generating structure might be geometrical, musical, modular, or fractal. Once we understand the nature of the structure underlying the design, we are able to "read" the meaning inherent in the architectural forms. The papers in this issue all explore themes of structure in different ways.
An important figure in the development of Nietzsche scholarship, Mazzino Montinari (1928-86) dedicated himself to the detailed study of the philosopher's writings. This lifetime of scholarship crystallized in Montinari's work as coeditor of the critical edition of Nietzsche's collected writings. Reading Nietzsche, now available in English for the first time, is a group of essays that grew out of this monumental work. In Reading Nietzsche Montinari tackles such subjects as the relationship between Nietzsche and Wagner, early drafts of Thus Spoke Zarathustra, and the philosopher's reputation among the Nazis and Marxists of the 1930s and 1940s. He also deals authoritatively with a number of figures who have had an unfortunate influence upon the way Nietzsche has been understood, from the chief Nazi interpreter of Nietzsche, Alfred Bäumler, to the chief Marxist interpreter, Georg Lukàcs, to Nietzsche's sister, Elisabeth.
In celebration of the 2009 International Year of Astronomy, this issue of the Nexus Network Journal is devoted to relationships between astronomy, mathematics and architecture. Ancient cultures looked to the heavens in order to identify timeless principles for their own creations. Knowledge gained in astronomy was transformed into culture through architecture and design. Papers in this issue look at how astronomy influenced architecture and urban design.
The history of design in Italy is explored in this authoritative and comprehensive work. Design periods include the era of Piranesi, the eclecticism of the 19th century, the futurism of the early 20th century, the dogmatic fascism of the interwar period, the designs of Pier Luigi Nervi and on to the present day.