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First multi-year cumulation covers six years: 1965-70.
Age-related macular degeneration (AMD) is the leading cause of irreversible central vision loss in developed countries.There have been rapid developments of therapies that today can halt or even reverse aspects of vision loss resulting from AMD among those most severely affected, and there is promise of future therapies that may prevent vision loss. This book provides an overview about AMD; an update on the current understanding of AMD, pathophysiology, the use of diagnostic tests, the management of both non-neovascular and neovascular AMD as well as future directions in treatment and its limitations. It also looks into the future with potential treatment options that are now under investigation in clinical trials.
Kabbalistic Manuscripts and Textual Theory uncovers the unstated assumptions and expectations of scribes and scholars who fashioned editions from manuscripts of Jewish mystical literature. This study offers a theory of kabbalistic textuality in which the material book the printed page no less than handwritten manuscripts serves as the site for textual dialogue between Jewish mystics of different periods and locations. The refashioning of the text through the process of reading and commenting that takes place on the page in the margins and between the lines blurs the boundaries between the traditionally defined roles of author, reader, commentator and editor. This study shows that kabbalists ...
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Alexander III was one of the most important popes of the Middle Ages and his papacy (1159-81) marked a significant watershed in the history of the Western Church and society. This book provides a long overdue reassessment of his papacy and his achievements, bringing together thirteen essays which review existing scholarship and present the latest research and new perspectives. Individual chapters cover topics such as Alexander's many contributions to the law of the Church, which had a major impact upon Western society, notably on marriage, his relations with Byzantium, and the extension of papal authority at the peripheries of the West, in Spain, Northern Europe and the Holy Land. But dominant are the major clashes between secular and spiritual authority: the confrontation between Henry II of England and Thomas Becket after which Alexander eventually secured the king's co-operation and the pope's eighteen-year conflict with the German emperor, Frederick I. Both the papacy and the Western Church emerged as stronger institutions from this struggle, largely owing to Alexander's leadership and resilience: he truly mastered the art of survival.
A revision of the author's thesis (doctoral)--Hebrew UniversityJerusalem, 2008.
From large cross-sectional studies of autopsy material, it seems as if a time course of Alzheimer's Disease, at least on average, can be mapped out: a pattern of hierarchical vulnerability for neuronal loss and neurofibrillary tangles beginning in medial temporal lobe structures proceeding through association areas. Plaques follow their own temporal course, with widespread cortical deposits occurring even early in a disease process. The whole process may well take twenty years, the first half of which may be without overt symptoms.
This book deals with the "Book of Splendor" (Sefer ha-Zohar), the greatest achievement of Kabbalah and one of the most influential sources of Western mysticism. This book offers a new interpretation of the Zohar, analyzing both its theoretical content and its historical context; it also brings the theory and the history together by indicating the personal and autobiographical elements in the Zohar's teachings. The author delves into the issues of the messianic elements of the Zohar, the way it was written, and its relationship to Christianity, Gnosticism, and Talmudic literature.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
This volume is a companion to the highly successful book published in association with the Journal of Alzheimer's Disease (JAD) on the centennial of Alzheimer's discovery: "Alzheimer's Disease: A Century of Scientific and Clinical Research". Instead of looking back, this collection, "Alzheimer's Disease: Advances for a New Century", will look forward. Using scientometric analysis the most promising developments since the Alzheimer Centennial in 2006 have been substantiated. While prior trends and advances in genetics, amyloid-β, tau, neuropathology, and oxidative stress continue as active areas, emergent areas impacting the transition from normal cognition to Alzheimer's disease such as diagnostic imaging, biomarkers, metabolism, and lifestyle (areas conceived only a few years ago) now dominate the debate.Invited contributors have summarized their landmark publications identified by our analysis and have put them into perspective, explaining the impetus behind the work, the contribution of the results to the field, and who played a role in the work.