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Challenges in Posterior Circulation Ischemic Stroke
The Topic Editors, Dr. Thanh Nguyen received research support from Medtronic, and Dr. Simon Nagel received research support from Cerenovus. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Coma and Disorders of Consciousness: An Overview
Coma and Disorders of consciousness (DoC) result from disruptions of neural systems and connections that regulate arousal and awareness. These terms encompass a spectrum of severity of illness due to a variety of modes and mechanisms of injury and lead to an enormous burden of morbidity and mortality. Additionally, Coma and DoC lead to a tremendous economic burden. For perspective, per 2010 USA data, the Center for Disease Control and Prevention estimated a societal cost of over $76 billion dollars from traumatic brain injury alone!
Antioxidant Enzyme
Free radicals are constantly formed in living cells and removed by antioxidant defenses. Antioxidant enzymes are the main line of defense against free radicals in animal and plant cells. Uncontrolled generation ROS are involved in a number of human disease states, including diabetes and cancer due to disturbance in cellular and molecular processes including cell growth, differentiation and proliferation. When cells are exposed to oxidative stress a defense system endorses the expression and regulation of number of antioxidant enzymes as a defense mechanism to protect them from the damage induced by free radicals. Based on this fact, the book "Antioxidant Enzymes" was designed to overview the importance of the antioxidant enzymes in human and plant cells against toxic free radicals, their relationship with several pathophysiologic processes and their possible therapeutic application.
Treatment-Related Stroke
This major new book examines all causes of treatment-related stroke, highlighting therapeutic approaches.
