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The aim of this book is to provide the researcher with important sample preparation strategies in a wide variety of analyte molecules, specimens, methods, and biological applications requiring mass spectrometric analysis as a detection end-point. In this volume we have compiled the contributions from several laboratories which are employing mass spectrometry for biological analysis. With the latest inventions and introduction of highly sophisticated mass spectrometry equipment sample preparation becomes an extremely important bottleneck of biomedical analysis. We have a goal of giving the reader several successful examples of sample preparation, development and optimization, leading to the success in analytical steps and proper conclusions made at the end of the day. This book is structured as a compilation of contributed chapters ranging from protocols to research articles and reviews. The main philosophy of this volume is that sample preparation methods have to be optimized and validated for every project, for every sample type and for every downstream analytical technique.
This volume focuses on the human exposures and medical effects studies in the SemipaiatinskJ Altai region of Siberia that were a consequence of the radioactive fallout from nuclear test explosions that took place at the Semipalatinsk Test Site of the former Soviet Union. It contains a detailed account of a NATO Advanced Research Workshop (ARW) devoted to the subject, and a selection of the papers presented. The title of the ARW was "Long-term Consequences of Nuclear Tests for the Environment and Population Health (SemipaiatinskJAltai Case Studies)". The estimated exposures to large numbers of people in the Altai lie in an important dose rate and dose domain. Hence the research reported herei...
Driven by the widespread growth of proteomic practices, protein separation techniques have been refined to minimize variability, optimize particular applications, and adapt to user preferences in the analysis of proteins. Separation Methods in Proteomics provides a comprehensive examination of all major separation techniques for proteomic
The aim of this book is to provide the researcher with important sample preparation strategies in a wide variety of analyte molecules, specimens, methods, and biological applications requiring mass spectrometric analysis as a detection end-point. In this volume we have compiled the contributions from several laboratories which are employing mass spectrometry for biological analysis. With the latest inventions and introduction of highly sophisticated mass spectrometry equipment sample preparation becomes an extremely important bottleneck of biomedical analysis. We have a goal of giving the reader several successful examples of sample preparation, development and optimization, leading to the success in analytical steps and proper conclusions made at the end of the day. This book is structured as a compilation of contributed chapters ranging from protocols to research articles and reviews. The main philosophy of this volume is that sample preparation methods have to be optimized and validated for every project, for every sample type and for every downstream analytical technique.
This book constitutes the refereed proceedings of the 10th International Conference on Optimization and Applications, OPTIMA 2019, held in Petrovac, Montenegro, in September-October 2019. The 35 revised full papers presented were carefully reviewed and selected from 117 submissions. The papers cover such topics as optimization, operations research, optimal control, game theory, and their numerous applications in practical problems of operations research, data analysis, and software development.
This book constitutes the refereed proceedings of the 12th International Conference on Optimization and Applications, OPTIMA 2021, held in Petrovac, Montenegro, in September - October 2021. Due to the COVID-19 pandemic the conference was partially held online. The 19 revised full papers presented were carefully reviewed and selected from 38 submissions. The papers are organized in topical sections on mathematical programming; global optimization; stochastic optimization; optimal control; mathematical economics; optimization in data analysis; applications.
This text reconsiders established interpretations of ethnic factors in the former Soviet Union and in contemporary Russia, arguing that: ethnicity is a complex phenomenon playing a multi-faceted role; ethnicity is the most accessible and understandable basis for political mobilization; ethnicity is a means of access to power and resources in a transforming society; and ethnicity is a therapy for the great trauma suffered by nationalities under previous regimes. executed by dominant groups like the Russians, and its periphery (or defensive) forms, subscribed to mainly by ethnic minorities with diminished status. Both have common features and are prone to conflicts which constitute a major obs...
This book constitutes the refereed proceedings of the 11th International Conference on Optimization and Applications, OPTIMA 2020, held in Moscow, Russia, in September-October 2020.* The 21 full and 2 short papers presented were carefully reviewed and selected from 60 submissions. The papers cover such topics as mathematical programming, combinatorial and discrete optimization, optimal control, optimization in economics, finance, and social sciences, global optimization, and applications. * The conference was held virtually due to the COVID-19 pandemic.