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Angiogenesis and Vascularisation
  • Language: en
  • Pages: 414

Angiogenesis and Vascularisation

The book presents the overview of the current knowledge in some fields of vascular biology, addressing cellular and molecular aspects of blood-vessel formation and their role in health and disease. The major factors involved in the formation of blood vessels are presented by scientists actively involved in this area of research. Special emphasis is put on the presentation of various molecular mechanisms not addressed in similar works to date. The book is divided into three parts. The first part describes the cells and mediators in angiogenesis. The significance of various populations of potential endothelial progenitors is particularly highlighted. The chapters of the second part focus on mo...

Wildlife Review
  • Language: en
  • Pages: 762

Wildlife Review

  • Type: Book
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  • Published: 1994
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  • Publisher: Unknown

None

Cardiac Development
  • Language: en
  • Pages: 296

Cardiac Development

The importance of the developmental approach for experimental and clinical cardiology is indisputable. Clinical-epidemiological studies have clearly shown that the risk factors of serious cardiovascular diseases, such as atherosclerosis and ischemic heart disease, are already present during the early phases of ontogenetic development. Furthermore, congenital cardiovascular malformations remain the single largest cause of infant mortality from congenital defects in industrial countries. It is therefore not surprising that the interest of theoretical and clinical cardiologists in the developmental approach keeps increasing. Advances in molecular biology accelerated this trend substantially. Th...

Modulation of Oxidative Stress
  • Language: en
  • Pages: 308

Modulation of Oxidative Stress

  • Type: Book
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  • Published: 2023-08-01
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  • Publisher: Elsevier

Modulation of Oxidative Stress: Biochemical, Physiological and Pharmacological Aspects explores the field using an interdisciplinary approach, including chemical, biological, physiological, pharmaceutical, pharmacological and physicochemical perspectives. The book is comprised of three main parts, with the first discussing the biochemical aspects of oxidative stress modulation. Other sections cover physiological and pathophysiological aspects on relevant conditions, including aging, neurological diseases, cerebral cavernous malformation, maternal and early-life malnutrition, Alzheimer’s disease, liver transplant, and cancer. Final content is dedicated to pharmacological aspects and include...

Heme Oxygenase
  • Language: en
  • Pages: 442

Heme Oxygenase

Heme oxygenase is an enzyme which breaks down heme, the iron-containing oxygen-carrying constituent of the red blood cells. Heme must be synthesised and degraded within an individual nucleated cell, as heme is essential for the maintenance of cellular homeostasis by sensing or using oxygen. Physiological heme degradation is catalysed by the two functional isozymes of heme oxygenase, heme oxygenase-1 (HO-1) and HO-2, yielding CO, iron, and biliverdin IX N. Heme oxygenase-1 (HO-1), has potent anti-inflammatory, anti-oxidant and anti-proliferative effects, is up-regulated by multiple stimuli and provides protection against oxidative stress. HO-1 also plays an important role in the regulation of cardiovascular function and is involved in many other diseases such as sickle cell disease. This new book brings together leading research from around the world in this field.

Heme Oxygenase in Biology and Medicine
  • Language: en
  • Pages: 542

Heme Oxygenase in Biology and Medicine

Heme oxygenase is rapidly taking its place as the centerpiece of multiple inter acting metabolic systems. Only 25 years ago heme oxygenase and its metabolic prod ucts appeared to be merely a simple metabolic system-one substrate, heme; one enzyme, heme oxygenase; and one set of products, iron to be recycled, and bilirubin and carbon monoxide to be disposed. From a group of about 25 people in 1974, as judged by attendance at various Gordon conferences, heme oxygenase has, in the year 2000, attracted working scientists-and clinicians I might add-by the hundreds and has produced referenced publications by the thousands. It is well-deserved attention. Heme oxygenase system is now similar to the ...

Thrombosis and Haemostasis
  • Language: en
  • Pages: 704

Thrombosis and Haemostasis

  • Type: Book
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  • Published: 2010
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  • Publisher: Unknown

None

Folia Biologica
  • Language: en
  • Pages: 100

Folia Biologica

  • Type: Magazine
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  • Published: 1997
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  • Publisher: Unknown

None

Folia Biologica
  • Language: en
  • Pages: 346

Folia Biologica

  • Type: Book
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  • Published: 1996
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  • Publisher: Unknown

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