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Life as It Is
"This book is an enjoyable and thought-provoking 'My Dinner With Bill Loomis'. He shows how respect for human life means acknowledging its ecological and evolutionary contexts. Molecular biology, he writes, is like Prometheus, giving us incredible tools for good or evil—and it's time that we grow up."—Scott F. Gilbert, Howard A. Schneiderman Professor of Biology, Swarthmore College "A wonderful journey through the very basis of life and how we live."—Lewis Wolpert, Professor of Biology as Applied to Medicine, University College, London "Advances in biology increasingly impinge on our everyday lives, challenging us with new interventions and ideas of what it means to be human. In this book, the distinguished scientist Bill Loomis takes us effortlessly through the biology we need to understand to come to our own opinions about these issues of great importance to each of us and to society as a whole."—Paul Nurse, President of Rockefeller University, Winner of the Nobel Prize in Physiology and Medicine
Epigenetics
The regulation of gene expression in many biological processes involves epigenetic mechanisms. In this new volume, 24 chapters written by experts in the field discuss epigenetic effects from many perspectives. There are chapters on the basic molecular mechanisms underpinning epigenetic regulation, discussion of cellular processes that rely on this kind of regulation, and surveys of organisms in which it has been most studied. Thus, there are chapters on histone and DNA methylation, siRNAs and gene silencing; X-chromosome inactivation, dosage compensation and imprinting; and discussion of epigenetics in microbes, plants, insects, and mammals. The last part of the book looks at how epigenetic mechanisms act in cell division and differentiation, and how errors in these pathways contribute to cancer and other human diseases. Also discussed are consequences of epigenetics in attempts to clone animals. This book is a major resource for those working in the field, as well as being a suitable text for advanced undergraduate and graduate courses on gene regulation.
Mosaic
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Life Illuminated
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Research Grants
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The Molecular Biology of Schizosaccharomyces pombe
The fission yeast Schizosaccharomyces pombe is the favoured tool of many productive research groups throughout the world, serving as a useful model for fundamental principles and mechanisms, such as genome organization, differential gene regulation, cell-cycle control, signal transduction, or cellular morphogenesis. This book collates the current state of knowledge derived from molecular studies in this simple eukaryotic microorganism. The entire sequence of its genome has been completed, emphasizing the comparative value and model status of this yeast. The individual chapters, highlighting up-to-date views on prominent aspects of molecular organization, were written by active research scientists, presenting the results of their investigations to other workers in neighbouring fields. This book intends to serve the fission yeast community as a handy source of reference for years to come. It will also be of particular value to the ever-increasing number of researchers starting to look into fission yeast affairs for comparative reasons from other platforms of molecular genetics and cell biology.
Current Catalog
First multi-year cumulation covers six years: 1965-70.
The Marriage Plot
The new novel from the bestselling author of Middlesex and The Virgin Suicides.
