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Brain Injury Medicine
Covers the full continuum from early diagnosis and evaluation through rehabilitation, post-acute care, and community re-entry. Includes assessment and treatment, epidemiology, pathophysiology, neuroanatomy, neuroimaging, the neuroscientific basis for rehabilitation, ethical and medicolegal issues, life-care planning, and more.
Understanding Traumatic Brain Injury
Progress in research on traumatic brain injury is presented in this book encompassing translational and clinical investigations. Observational and interventional studies are discussed by leading investigators of TBI in adults and children. Contributors from various countries provide a global perspective on this worldwide health problem.
Acute Care Neuroconsultation and Neurorehabilitation Management
This book is a comprehensive resource on acute neurorehabilitation consultations. When a patient first undergoes a traumatic brain or acquired spinal cord injury, an immediate consultation is needed with a rehabilitation specialist. In-depth literature reviews, practice guidelines, and case studies offer in-depth, practical coverage of the complete neurorehabilitation consultation with information on specific testing tools and metrics. The acute care consultant works in concert with other physicians and medical professionals, so throughout the text considerations on how to best organize the team to maximize care is carefully considered. Chapters also explore acute neurological sequelae, including arousal and stimulation, sleep, agitation, spasticity, and seizure prevention, for which an acute care consultant could provide important insight, treatment, and future management recommendations. The book concludes with advice on how to best transition patients from acute to long-term care, including patient prognostication and family education. This is an ideal guide for physiatrists and neurologists aiming to maximize recovery outcomes for their patients.
Adenosine
Homeostasis of key metabolites and metabolic health affects all bodily systems. Not surprisingly, altered metabolic function is associated with a wide spectrum of dysfunctions in the central nervous system – including developmental disorders, acute nervous system injury, and neurodegenerative disorders. Accordingly, metabolism-based therapies offer significant promise as new category of treatment options designed to limit, delay or reverse the disease process by reconstructing homeostatic functions. Increasingly it is appreciated that restoring metabolic health could promote normal nervous system activity, and improve behavior and cognition. Adenosine: A Key Link Between Metabolism and Cen...
Homeostatic Control of Brain Function
Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders. Each disorder has multiple comorbidities - with some crossing over several conditions - and often disease-specific treatments remain elusive. When current pharmacological therapies result in ineffective and inadequate outcomes, therapies to restore and maintain homeostatic functions can help improve brain health, no matter the diagno...
Neurocritical Care
Neurocritical Care provides 'at the bedside' guidance on the medical knowledge and technical skills required to care for critically ill patients with neurologic conditions. Part of the Pittsburgh Critical Care Medicine series, this compact volume is an ideal reference for physicians and trainees working in either a general ICU or specialty Neuro ICU unit.
Brain Injury Medicine, 2nd Edition
This book is a clear and comprehensive guide to all aspects of the management of traumatic brain injury-from early diagnosis and evaluation through the post-acute period and rehabilitation. An essential reference for physicians and other health care professionals who work with brain injured patients, the book focuses on assessment and treatment of the wider variety of clinical problems these patients face and addresses many associated concerns such as epidemiology, ethical issues, legal issues, and life-care planning. Written by over 190 acknowledged leaders, the text covers the full spectrum of the practice of brain injury medicine including principles of neural recovery, neuroimaging and neurodiagnostic testing, prognosis and outcome, acute care, rehabilitation, treatment of specific populations, neurologic and other medical problems following injury, cognitive and behavioral problems, post-traumatic pain disorders, pharmacologic and alternative treatments, and community reentry and productivity.
Metabolic Control of Brain Homeostasis
Brain function is under metabolic control, which in turn determines the equilibrium of homeostatic systems that affect neuronal and glial networks on the molecular, cellular, and systems levels. The collection of articles ranges from molecules and mechanisms involved in regulating homeostasis and neuronal excitability to therapeutic mechanisms tailored to restore homeostatic function. It also features neurological diseases and novel treatment approaches that are based on metabolic and homeostatic interventions. Together, the collection of articles outlines novel strategies to restore brain function in neurology and highlights limitations of conventional pharmacological approaches. We suggest that restoration of molecular and biochemical networks could lead to a new era of therapeutic opportunities.
Biomarkers of Brain Injury and Neurological Disorders
This book explores the recent advances in the techniques and platforms used in biomarker research that have revolutionized the way we study, diagnose, and treat brain injury conditions. The contributors describe different biomarker studies pertaining to brain injury and other neurological disorders and analyze the different models and technologies used to identify these biological markers. The book includes findings from "Omics research" that have been utilized to decipher and identify such biomarkers. It discusses protein, microRNA, and altered gene profiles and reviews neurological disorders such as multiple sclerosis, Charcot-Marie-Tooth disease, and prion and Alzheimer’s disease.
Braddom's Physical Medicine and Rehabilitation
The most-trusted resource for physiatry knowledge and techniques, Braddom's Physical Medicine and Rehabilitation remains an essential guide for the entire rehabilitation team. With proven science and comprehensive guidance, this medical reference book addresses a range of topics to offer every patient maximum pain relief and optimal return to function. In-depth coverage of the indications for and limitations of axial and peripheral joints through therapies enables mastery of these techniques. Optimize the use of ultrasound in diagnosis and treatment. A chapter covering PM&R in the international community serves to broaden your perspective in the field. Detailed illustrations allow you to gai...
