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Artificial Intelligence in PET/CT Oncologic Imaging
This book presents artificial intelligence applications that may help in detecting disease, defining tissue characterization (benign vs malignant), staging and correlation with molecular biomarkers. Originally positioned as a means for noninvasive molecular phenotyping and quantification in the 1970s, PET's technological improvements in the 2000s generated renewed interest in quantification, which has grown over the last five years. This progress is parallel with the development of Artificial intelligence (AI) systems for Oncology which aim at providing the best possible treatment to patients suffering from lung, breast, brain, prostate, liver and other types of cancer. The chapters provide an overview of the use of AI in PET/CT imaging for various types of cancer, and it will be an invaluable tool especially for nuclear medicine physicians and oncologists.
The Cinema of Latin America
The Cinema of Latin America is the first volume in the new 24 Frames series of studies of national and regional cinema. In taking an explicitly text-centered approach, the books in this series offer a unique way of considering the particular concerns, styles and modes of representation of numerous national cinemas around the world. This volume focuses on the vibrant practices that make up Latin American cinema, a historically important regional cinema and one that is increasingly returning to popular and academic appreciation. Through 24 individual concise and insightful essays that each consider one significant film or documentary, the editors of this volume have compiled a unique introduction to the cinematic output of countries as diverse as Brazil, Argentina, Cuba, Mexico, Bolivia, Chile and Venezuala. The work of directors such as Luis Buñuel, Thomas Guiterrez Alea, Walter Salles, and Alfonso Arau is discussed and the collection includes in-depth studies of seminal works as such Los Olvidados, The Hour of the Furnaces, Like Water For Chocolate, Foreign Land, and Amoros Perros.
Romance Linguistics
This volume contains a selection of refereed and revised papers, originally presented at the 32nd Linguistics Symposium on Romance Languages, dealing with linguistic theory as applied to the Romance languages, and on empirical studies on the acquisition of Romance, with studies on Romanian, French, Spanish, Portuguese, Italian, Romansch and Latin. The theoretical section contains contributions concentrating on specific properties of Romance at the syntax/semantics interface, on morphosyntactic issues, on subject licensing and case, and on phonology. The acquisition section includes contributions on first, bilingual and second language acquisition of functional structure, word structure, quantification and stress.
Oral Bioavailability and Drug Delivery
ORAL BIOAVAILABILITY AND DRUG DELIVERY Improve the performance and viability of newly-developed and approved drugs with this crucial guide Bioavailability is the parameter which measures the rate and extent to which a drug reaches a user’s circulatory system depending on the method of administration. For example, intravenous administration produces a bioavailability of 100%, since the drugs are injected directly into the circulatory system; in the case of oral administration, however, bioavailability can vary widely based on factors which, if not properly understood, can result in a failure in drug development, adverse effects, and other complications. The mechanics of oral bioavailability...
Carbohydrate-Based Vaccines and Immunotherapies
The fundamental science and the latest developments in carbohydrate-based vaccines The relatively new field of glycoimmunology has emerged from the marriage of glycobiology and immunology, in recognition of the important role carbohydrates play as antigenic determinants. Carbohydrate-Based Vaccines and Immunotherapies comprehensively reviews the state of this exciting field, offering a single source for both the fundamental science and the latest developments. With contributions by leading experts, this resource covers the design, synthesis, evaluation, and applications of various carbohydrate-based vaccines, including polysaccharides, neoglycoproteins, and neoglycolipids. The text approache...
Drug Delivery
Following its successful predecessor, this book covers the fundamentals, delivery routes and vehicles, and practical applications of drug delivery. In the 2nd edition, almost all chapters from the previous are retained and updated and several new chapters added to make a more complete resource and reference. • Helps readers understand progress in drug delivery research and applications • Updates and expands coverage to reflect advances in materials for delivery vehicles, drug delivery approaches, and therapeutics • Covers recent developments including transdermal and mucosal delivery, lymphatic system delivery, theranostics • Adds new chapters on nanoparticles, controlled drug release systems, theranostics, protein and peptide drugs, and biologics delivery
Chemosensors
A thorough, accessible, and general overview of chemosensors Providing a comprehensive overview of chemosensors organic molecules designed to bind and sense small molecules or metal ions and their applications, Chemosensors: Principles, Strategies, and Applications is an accessible one-stop resource for analysts, clinicians, and graduate students studying advanced chemistry and chemosensing. Chemosensors function on a molecular level, generating a signal upon binding. The book reviews their synthesis, design, and applications for detecting biological and organic molecules as well as metal ions. The text highlights applications in drug discovery and catalyses that have not been well covered e...
Carbohydrate Recognition
This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition.
Drug-Drug Interactions in Pharmaceutical Development
Drug-Drug Interactions in Pharmaceutical Development comprehensively reviews the relevant science, industrial practice, and regulatory agency positions on drug-drug interactions. It focuses on the evaluation of potential drug-drug interactions, allowing researchers to address risk factors before a drug is put to market. The book covers both clinical and nonclinical aspects for understanding drug-drug interactions as well as in vitro and in vivo studies for use in studying interactions at the drug discovery stage.
Dendrimer-Based Drug Delivery Systems
The opportunities and challenges of using dendrimers to improve drug delivery Among pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a dendrimer increases when it has a positive charge. If this property can be applied effectively, dendrimers have enormous potential in drug delivery systems, directly supplying medication to targeted human organs. With contributions from an international team of pioneers and experts in dendrimer research, this book provides a comprehensive overview of the latest research efforts in designing and optimizing dendrimer-based drug de...
