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Polyglutamine Disorders
This book provides a cutting-edge review of polyglutamine disorders. It primarily focuses on two main aspects: (1) the mechanisms underlying the pathologies’ development and progression, and (2) the therapeutic strategies that are currently being explored to stop or delay disease progression. Polyglutamine (polyQ) disorders are a group of inherited neurodegenerative diseases with a fatal outcome that are caused by an abnormal expansion of a coding trinucleotide repeat (CAG), which is then translated in an abnormal protein with an elongated glutamine tract (Q). To date, nine polyQ disorders have been identified and described: dentatorubral-pallidoluysian atrophy (DRPLA); Huntington’s dise...
Compliance
"(...)Neste contexto, a obra já nasce atual e relevante, pois é preciso verificar, rectius, investigar como as corporações privadas e os organismos públicos estão lidando com estes desafios na sua gestão interna e nas suas relações com seus investidores/administrados. Como elaborar, executar e fiscalizar programas de integridade em organizações complexas, de modo que todos os executivos e empregados (do menor ao maior nível) estejam a eles sujeitos e possam por ele ser punidos, se necessário. A primeira parte da obra, de cunho teórico, reúne 14 (catorze) artigos sobre as mais diversas áreas do conhecimento em que o tema transita, não apenas na ciência jurídica, mas também...
Interaction Between Neurons and Glia in Aging and Disease
A superb source of reference reviews as well as a concise overview of the functional cross-talk between neurons and glial cells, this book also focuses on microglia and inflammation in the aging brain and in neurological disorders. The scientific spectrum covered by this book is of key interest, and is recognized by the scientific community as a major competitive area with critical implications for human health.
The Three Marias
None
Sustainable Crop Production
This book includes twenty-one comprehensive chapters addressing various soil and crop management issues, including modern techniques in enhancing crop production in the era of climate change. There are a few case studies and experimental evidence about these production systems in specific locations. Particular focus is provided on the state-of-the-art of biotechnology, nanotechnology, and precision agriculture, as well as many other recent approaches in ensuring sustainable crop production. This book is useful for undergraduate and graduate students, teachers, and researchers, particularly in the fields of crop science, soil science, and agronomy.
Best Practice 3
Emma Nardi, Introduction; Anja Bellmann, Stefan Bresky, Bernd Wagner, Early Childhood Education in Museums. Exploring History in the Deutsches Historisches Museum; Anna Asoyan, Armine Grigoryan, The Museum is the Guest of the School; Ana Luisa Nossar, Branca Pimentel, Elaine Fontana, Marina Herling, Maria Carolina Machado, Paula Selli, Babies at the Museum? At Segall, that’s happening!; María Antonieta Sibaja Hidalgo, Descubrir, experimentar, construir…; Ernesta Todisco, Summer Camp for children. Promoting the knowledge of the museum; Niko Bos, Developing Look & Learn cards; Annemies Broekgaarden, History adventure! You and the Golden Age; Anne-Sophie Grassin, Un dimanche avec des étud...
Advances in Psychedelic Medicine
Researchers, program administrators, and practicing clinicians explain the most recent developments in using psychedelic substances to treat psychological, physiological, and social problems. More than a decade ago, the U.S. government lifted its ban on all testing of psychedelic substances. Winkelman and Sessa now provide updated scientific research and applications of these substances, now moving into approved categories of medicine. The text is an up-to-date assessment of the latest advances in the field of psychedelic medicine, covering the use of LSD, psilocybin, MDMA, ayahuasca, and other substances to augment psychotherapies for a range of disorders. It discusses medical and psychiatr...
Innovation, Engineering and Entrepreneurship
This book presents endeavors to join synergies in order to create added value for society, using the latest scientific knowledge to boost technology transfer from academia to industry. It potentiates the foundations for the creation of knowledge- and entrepreneurial cooperation networks involving engineering, innovation, and entrepreneurship stakeholders. The Regional HELIX 2018 conference was organized at the University of Minho’s School of Engineering by the MEtRICs and Algoritmi Research Centers, and took place in Guimarães, Portugal, from June 27th to 29th, 2018. After a rigorous peer-review process, 160 were accepted for publication, covering a wide range of topics, including Control...
Antibiotic Drug Resistance
This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies
