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Innovative Pharmacometric Approaches to Inform Drug Development and Clinical Use
Pharmacometrics represents a strategy to optimize and rationalize decision-making process integrating information on drug behavior, pharmacological response, and disease progression both in the drug development phases and in their clinical use. Pharmacometrics focuses on characterizing the pharmacokinetic and pharmacodynamic behavior of one or several active ingredients through the development of mathematical and statistical models that allow characterizing both the average behavior in the population and the different sources of variability. Currently, pharmacometrics has transformed drug development and therapeutic use paradigm, which yield to the recognition by the main regulatory agencies (FDA, EMA, and PMDA).
Innovation in Pharmacy: Advances and Perspectives. September 2018
This book contains the summaries of the "Innovation in Pharmacy: Advances and Perspectives" that took place in Salamanca (Spain) in September 2018. The early science of chemistry and microbiology were the source of most drugs until the revolution of genetic engineering in the mid 1970s. Then biotechnology made available novel protein agents such as interferons, blood factors and monoclonal antibodies that have changed the modern pharmacy. Over the past year, a new pharmacy of oligonucleotides has emerged from the science of gene expression such as RNA splicing and RNA interference. The ability to design therapeutic agents from genomic sequences will transform treatment for many diseases. The...
«Aprendizaje del ejercicio profesional de la atención farmacéutica en un mundo virtual»
En el momento actual nos encontramos en una situación de importantes cambios, tanto en lo que respecta al modelo de Espacio Europeo de Educación Superior, que está suponiendo el replanteamiento de los modelos y estrategias docentes empleados hasta la fecha, como en lo relativo a la implantación, en el último ciclo de Educación Primaria y primer ciclo de Educación Secundaria, del Programa Escuela 2.0, por parte del gobierno español. Ambos hechos implican un cambio de cultura que concierne tanto al docente como a los estudiantes y a la propias instituciones como tales. La Escuela 2.0 supone, por ejemplo, explorar nuevos enfoques metodológicos y herramientas que pueden emplearse con fi...
Polo in Argentina
This work--the first of its kind in more than sixty years--covers polo in Argentina, from its beginnings in the 1870s to the summer of 2013. The history of the early pioneers is constructed with data not previously published, gathered from contemporary sources. International competitions are covered and include the Olympic Games, the Cup of the Americas and the World Championships. Particular attention is given to the major clubs, the Argentine and Hurlingham Open Championships, and the National Handicap Tournament. Several of the elite players merit individual or family mini-biographies. Myths in Argentine polo are also debunked, based upon careful analysis of contemporary sources. Travels abroad by Argentine teams are fully described as are the foreign teams that competed in Argentina. The work is enhanced by the author's personal observation of significant events and friendship with many of the participants.
Proceedings of the International Congress of Mathematicians
The International Congress of Mathematicians (ICM) is held every four years. It is a major scientific event, bringing together mathematicians from all over the world and demonstrating the vital role that mathematics play in our society. In particular, the Fields Medals are awarded to recognize outstanding mathematical achievement. At the same time, the International Mathematical Union awards the Nevanlinna Prize for work in the field of theoretical computer science. The proceedings of ICM 2006, published as a three-volume set, present an overview of current research in all areas of mathematics and provide a permanent record the congress. The first volume features the works of Fields Medallists and the Nevanlinna Prize winner, the plenary lectures, and the speeches and pictures of the opening and closing ceremonies and award sessions. The other two volumes present the invited lectures, arranged according to their mathematical subject.
Diccionario terminológico de las ciencias farmacéuticas
El Diccionario Terminológico de Ciencias Farmacéuticas de la Real Academia Nacional de Farmacia y Editorial Ariel consta de dos partes. La primera (inglés-español) tiene unos 15.000 términos, y la segunda (español-inglés), más de 13.000. Todos ellos han sido ordenados en torno a los siguientes 25 campos semánticos: 1. Análisis farmacéutico (absorbance ─absorbancia─, bacteria ─bacteria─, etc.). 2. Asistencia sanitaria (discharge ─alta [hospitalaria]─, relapse ─recaer─, etc.). 3. Bioética (code of conduct ─código deontológico─, living will ─testamento vital─, etc.). 4. Biofarmacia (bioavailability ─biodisponibilidad─, route ─vía de administración...
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The Mexican Masked Wrestler and Monster Filmography
Any on-screen schmuck can take down a wolfman with a silver bullet. It takes a certain kind of hero to hoist that wolfman overhead into an airplane spin, follow with a body slam, drop an atomic elbow across his mangy neck, leg-lock him until he howls, and pin his furry back to the mat for a three-count. It takes a Mexican masked wrestler. Add a few half-naked vampire women, Aztec mummies, mad scientists, evil midgets from space, and a goateed Frankenstein monster, and you have just some of the elements of Mexican masked wrestler and monster movies, certainly among the most bizarre, surreal and imaginative films ever produced. This filmography features some of the oddest cinematic showdowns e...
«El cuaderno de equipo: Una experiencia desarollada en wiki-site en grupos colaborativos»
En el momento actual nos encontramos en una situación de importantes cambios, tanto en lo que respecta al modelo de Espacio Europeo de Educación Superior, que está suponiendo el replanteamiento de los modelos y estrategias docentes empleados hasta la fecha, como en lo relativo a la implantación, en el último ciclo de Educación Primaria y primer ciclo de Educación Secundaria, del Programa Escuela 2.0, por parte del gobierno español. Ambos hechos implican un cambio de cultura que concierne tanto al docente como a los estudiantes y a la propias instituciones como tales. La Escuela 2.0 supone, por ejemplo, explorar nuevos enfoques metodológicos y herramientas que pueden emplearse con fi...
