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The Treatment of Bipolar Disorder
Bipolar disorder is a chronic and debilitating mental illness affecting a significant proportion of the world's population. It is associated with significant impairments in health-related quality of life and psychosocial functioning, and has significant illness-related morbidity and heightened mortality rates due to medical comorbidities and suicide. The management of this disorder requires a complex combination of pharmacological and psychosocial interventions which can be challenging for clinicians. Written by world experts in the field of bipolar disorder, The Treatment of Bipolar Disorder: Integrative Clinical Strategies and Future Directions provides readers with a concise and comprehen...
The Search for Antidepressants - An Integrative View of Drug Discovery
Major depressive disorder (MDD) is a prevalent, chronic, and recurring mental disorder. This disorder is a leading source of disability worldwide, and is associated with excess mortality rates. Currently approved antidepressants primarily enhance, or otherwise modulate monoaminergic neurotransmission, without curing the disease. Evidence indicates that only one third of patients with MDD achieve remission after treatment with a first-line antidepressant agent. Research in the past two decades has provided valuable insights into the pathophysiological understanding of MDD. However, there is an acknowledged ‘translational gap’ in the field, and few genuinely novel antidepressants have been...
Treatment-resistant Mood Disorders
Treatment-resistant major depression and bipolar disorder are highly prevalent and disabling conditions associated with substantial morbidity and mortality. Providing a concise view of the current definitions, assessment and evidence-based management of such disorders, this work reviews novel therapeutic targets, which may enhance the future therapeutic armamentarium of clinicians.
Fugitive Freedom
The curious tale of two priest impersonators in late colonial Mexico Cut loose from their ancestral communities by wars, natural disasters, and the great systemic changes of an expanding Europe, vagabond strangers and others out of place found their way through the turbulent history of early modern Spain and Spanish America. As shadowy characters inspiring deep suspicion, fascination, and sometimes charity, they prompted a stream of decrees and administrative measures that treated them as nameless threats to good order and public morals. The vagabonds and impostors of colonial Mexico are as elusive in the written record as they were on the ground, and the administrative record offers little ...
Understanding Depression
This book, in two volumes, focuses on contemporary issues and dilemmas in relation to depression. The aim is to equip readers with an up-to-date understanding of the clinical and neurobiological underpinnings of depression and their relation to clinical manifestations and the development of more effective treatments. This first volume is devoted specifically to biomedical and neurobiological issues. Detailed information is presented on a wide range of topics, including genetics, molecular and cellular biology, and aspects at the neural circuit and multicellular system levels. Readers will gain a deeper appreciation of the factors and interactions underlying individual variation in responsiveness to stress and vulnerability to depression, as well as a clear understanding of potential treatment targets and causes of treatment resistance based on the latest research. A concluding section considers progress towards precision psychiatry and gender and cultural differences in depression. The companion volume is dedicated to clinical and management issues in depression. Understanding Depression will be an excellent source of information for both researchers and practitioners in the field.
Cognition in Mood Disorders
International Society for Affective Disorders (ISAD) exists to promote research into the mood (affective) disorders through all relevant scientific disciplines, including genetics, neuroscience and the social and behavioural sciences. Inter-disciplinary research approaches are particularly highly valued by the society. www.isad.org.uk
Devout
"In this revelatory memoir seeking to bridge the gap between science and spirituality, Anna Gazmarian tells the story of how her Evangelical upbringing in North Carolina, provided an inadequate framework to understand the mental health diagnosis she received, and the work she had to do to find proper medical treatment while also maintaining her faith. When Anna is diagnosed with bipolar disorder in 2011, she s faced with a conundrum: while the diagnosis provides clarity about her manic and depressive episodes, growing up in an Evangelical community means that her diagnosis is regarded as an affliction of the spirit rather than a medical condition. Over ten years, we follow Anna on her journey to reframe her understanding of mental health to expand the limits of what her religious faith can offer."--Provided by publisher.
Mental Disorders in Primary Care
An invaluable guide to psychiatric presentation, diagnosis and treatment in a primary care setting.
Cognitive Enhancement in CNS Disorders and Beyond
Cognitive Enhancement in CNS Disorders and Beyond compiles a series of educational and thought-provoking chapters from the world's leading cognitive and clinical scientists to describe the latest research on methods for improving cognition in healthy people and those with cognitive disorders.
