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A comprehensive volume devoted to startle modification.
Jenefer Robinson uses modern psychological and neuroscientific research on the emotions to study our emotional involvement with the arts.
Workflow-based Process Controlling Systems provide companies with the ability to measure the operational performance of their business processes in a timely and accurate fashion. The combination of workflow audit trails with data warehouse technology and operational business data allows for complex analyses that can support managers in their assessment of an organization's performance. The increasing maturity of business process management and data warehouse systems enables the design and development of advanced process-oriented management information systems. Michael zur Muehlen discusses the integration of workflow audit trail data with existing data warehouse structures and develops a ref...
This book examines how interactions between organizations within the international climate change movement shape tactics and outcomes in climate change negotiations.
This research volume serves as a comprehensive resource for psychophysiological research on media responses. It addresses the theoretical underpinnings, methodological techniques, and most recent research in this area. It goes beyond current volumes by placing the research techniques within a context of communication processes and effects as a field, and demonstrating how the real-time measurement of physiological responses enhances and complements more traditional measures of psychological effects from media. This volume introduces readers to the theoretical assumptions of psychophysiology as well as the operational details of collecting psychophysiological data. In addition to discussing specific measures, it includes brief reviews of recent experiments that have used psychophysiological measures to study how the brain processes media. It will serve as a valuable reference for media researchers utilizing these methodologies, or for other researchers needing to understand the theories, history, and methods of psychophysiological research.
The field of N-heterocyclic carbenes, whether in transition-metal catalysis or organocatalysis, is rapidly evolving towards applications, but is also still very active on the catalyst development front. Significant advances have been made over the past two decades and the development of these reactions has dramatically improved the efficiency of organic synthesis. N-Heterocyclic carbene based catalysts are now widely applied in the area of synthesis of both natural products and therapeutic agents. Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis presents the most commonly used and significant metal- or non-metal-catalyzed reactions for modern organic synthesis. The basic principles and current state-of-the-art of the methods are covered. Scope, limitations, and mechanism of these reactions are discussed and key experimental procedures are included. Typical examples of target synthesis are often provided to show the utility and inspire further applications.
Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics, GPCRs and the identification of novel allosteric binding pockets. The first fragment-derived drug was recently approved for the treatment of melanoma. It is hoped that this approval is just the beginning of the many drugs yet to be discovered using this fascinating technique. This book is written from a Chemist's perspective and comprehensively assesses the impact of fragment-based drug discovery on a wide variety of areas of medicinal chemistry. It will prove to be an invaluable resource for medicinal chemists working in academia and industry, as well as anyone interested in novel drug discovery techniques.