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Animal Models for Human Cancer
Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for cancer therapies, addressing the widely recognized lack of reliable and reproducible results. Following a short historical introduction and a discussion of the ethics surrounding animal experiments, the book describes correct study design as well as the handling and housing of animals. It then goes on to describe the animal models available for different cancer types, from natural cancer models in mice and dogs to humanized animals. An evaluation of previously unpublished long-term data from the Swiss canine and feline cancer registry is also included. The final part of the book reviews the lessons learned over the last decade on how to interpret data from animal studies for improving human therapy and gives recommendations for future drug development.
21st Century Advanced Carbon Materials for Engineering Applications
Advanced carbon materials such as graphene, fullerenes, hierarchical carbon, and carbon nanotubes (CNTs) have exceptional physical properties, making them useful for several applications in fields ranging from energy and industry to electronics and drug delivery. This book includes comprehensive information on fabrication, emerging physical properties, and technological applications of advanced carbon materials. Over three sections, chapters cover such topics as advanced carbon materials in engineering, conjugation of graphene with other 2D materials, fabrication of CNTs and their use in tissue engineering and orthopaedics, and advanced carbon materials for sustainable applications, among others.
Ultrastructural Pathology
Ultrastructural Pathology, Second Edition is a comprehensive reference on electron microscopy of pathologic tissue in animals and humans. Now presented in an atlas format for easier identification of organelles, the text is designed to bridge the gap between what is seen in the electron microscope at the cellular level and what the pathologist encounters in the postmortem room. New to this edition are sections on diagnostic electron microscopy, providing information on specialized technologies for electron microscopy, and invertebrate pathology. Emphasizing comparative pathology, the book explains and integrates all aspects of cellular changes in lesions occurring from natural or experimental disease.
Intracellular Pathogens I
A current review of basic research on Chlamydiales biology and pathogenesis in one comprehensive volume. • Details the scientific knowledge about how these obligate intracellular bacteria invade, survive and replicate inside eukaryotic cells. • Describes the spectrum of disease caused by an infection including protective and pathologic immune responses. • Describes the latest developments, including genomics and biomathematical modeling, and progress towards genetic tools and a vaccine. • Serves as a significant research book for scientists, physicians, medical students, public health professionals, epidemiologists, biocomputational scientists and government policy makers.
BIODIVERSITY AND MICROBIAL ECOLOGY
The first unicellular microorganisms would have appeared on our planet, about 4 billion years ago. Since then, these microorganisms have developed into various forms of life such as bacteria, fungi, algae, protozoa and viruses, animals, plants ... etc. Microorganisms are found in all ecosystems (water, air, soil, food ... etc.). Some microorganisms can associate with plants or animals and maintain a relationship of symbiosis, commensalism or parasitism
Water-filtered Infrared A (wIRA) Irradiation
The aim of this open access book is to provide a unique, timely, critical and comprehensive compilation of more than 30 years of robust international experimental and clinical research related to the basic science and therapeutic application of water-filtered infrared-A (wIRA) and hyperthermia in oncology, psychiatry (depression), musculoskeletal disorders, dermatology, infectiology, and surgery. This is an internationally absolutely unique attempt which publication is timely and of great interest in medical as well as in natural sciences. The aim is to enhance communication and advance the use of heat therapy for patient benefit, and to generate an environment in which anyone with an intere...
