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Drug-Acceptor Interactions
Drug-Acceptor Interactions: Modeling theoretical tools to test and evaluate experimental equilibrium effects suggests novel theoretical tools to test and evaluate drug interactions seen with combinatorial drug therapy. The book provides an in-depth, yet controversial, exploration of existing tools for analysis of dose-response studies at equilibrium or steady state. The book is recommended reading for post-graduate students and researchers engaged in the study of systems biology, networks, and the pharmacodynamics of natural or industrial drugs, as well as for medical clinicians interested in drug application and combinatorial drug therapy. Even people without mathematical skills will be able to follow the pros and cons of reaction schemes and their related distribution equations. Chapter 9 is a hands-on guide for software to plot, fit and analyze one’s own data.
Genetic Enhancement of Crops for Tolerance to Abiotic Stress: Mechanisms and Approaches, Vol. I
Abiotic stresses such as drought (water deficit), extreme temperatures (cold, frost and heat), salinity (sodicity) and mineral (metal and metalloid) toxicity limit productivity of crop plants worldwide and are big threats to global food security. With worsening climate change scenarios, these stresses will further increase in intensity and frequency. Improving tolerance to abiotic stresses, therefore, has become a major objective in crop breeding programs. A lot of research has been conducted on the regulatory mechanisms, signaling pathways governing these abiotic stresses, and cross talk among them in various model and non-model species. Also, various ‘omics’ platforms have been utilize...
Ecotoxicology and Genotoxicology
The potential impact of anthropogenic pollutants such as agrochemicals on the environment is of global concern. Increasing use of certain compounds can result in contamination of food, water and atmospheric systems and in order to combat this pollution it is important to be able to accurately monitor the short and long term effects. This book describes the latest non-traditional terrestrial species models used as indicators of the toxic effects of environmental pollutants. The book enables understanding of the effects of pollutants in non-target species, and therefore enables analysis of the effects on ecosystems. This book will be of interest to anyone interested in developing new biomarker species with high degrees of ecological relevance. It will serve as a useful resource for regulatory and research toxicologists, particularly those interested in soil screening and the effects of pollutants on wildlife and insects and their use as biological indicators.
River Networks as Ecological Corridors
A summary of state-of-the-art research on how the river environment impacts biodiversity, species invasions, population dynamics, and the spread of waterborne disease. Blending laboratory, field and theoretical studies, it is the go-to reference for graduate students and researchers in river ecology, hydrology, and epidemiology.
Girls & Sex - Navigating the Complicated New Landscape
'If you're going to talk about women in the 21st century, you MUST read Peggy Orenstein's Girls & Sex.' - CAITLIN MORAN, author of How to Be a Woman *TIME Top 10 non-fiction books of 2016* *Amazon Best Non-fiction of 2016* A generation gap has emerged between parents and their daughters. Mothers and fathers have little idea about the pressures and expectations they face or how they feel about them. Drawing on in-depth interviews with young women and a wide range of psychologists and experts, renowned journalist and bestselling author Peggy Orenstein goes where most others fear to tread, pulling back the curtain on the hidden truths and hard lessons of girls’ sex lives in the modern world.
PET/CT in Radiotherapy Planning
This pocket book offers a succinct but comprehensive overview of the role of PET/CT in radiotherapy planning. Individual chapters are devoted to specific application of the technique to particular tumor types, including non-small cell lung, gastrointestinal, head and neck squamous cell, prostate, gynecological, and pediatric tumors. Helpful information is also presented on the practical implementation of PET/CT in routine oncological practice. Technical and logistical issues are discussed, and guidance provided on potential problems and pitfalls and available solutions. The book will be invaluable in assisting readers to exploit PET/CT’s ability to significantly improve delineation of tumor tissue through the addition of metabolic information to structural imaging data, thereby avoiding unnecessary radiation injury and associated complications while enhancing therapeutic effects and minimizing the risk of marginal recurrences. It is published within the Springer series Clinicians’ Guides to Radionuclide Hybrid Imaging, compiled under the auspices of the British Nuclear Medicine Society.
The Rivals and Other Stories
A major literary figure and frequent contributor to the Yiddish-language newspaper Forverts from the 1920s to the mid-1930s, Jonah Rosenfeld was recognized during and after his lifetime as an explorer of human psychology. His work foregrounds loneliness, social anxiety, and people’s frustrated longing for meaningful relationships—themes just as relevant to today’s Western society as they were during his era. The Rivals and Other Stories introduces nineteen of Rosenfeld’s short stories to an English-reading audience for the first time. Unlike much of Yiddish literature that offers a sentimentalized view of the tight knit communities of early twentieth-century Jewish life, Rosenfeld’...
Learn Electronics with Arduino
This book is your introduction to to physical computing with the Arduino microcontroller platform. No prior experience is required, not even an understanding of basic electronics. With color illustrations, easy-to-follow explanations, and step-by-step instructions, the book takes the beginner from building simple circuits on a breadboard to setting up the Arduino IDE and downloading and writing sketches to run on the Arduino. Readers will be introduced to basic electronics theory and programming concepts, as well as to digital and analog inputs and outputs. Throughout the book, debugging practices are highlighted, so novices will know what to do if their circuits or their code doesn't work f...
The Sad End of Policarpo Quaresma
'The seed of madness exists in all of us and with no warning may attack, overpower, crush and bury us ... ' Policarpo Quaresma - fastidious civil servant, dedicated patriot, self-styled visionary - is a defender of all things Brazilian, full of schemes to improve his beloved homeland. Yet somehow each of his ventures, whether it is petitioning for Brazil's national language to be changed, buying a farm to prove the richness and fertility of the land, or offering support to government forces as they suppress a military revolt - results in ridicule and disaster. Quixotic and hapless, Quaresma's dreams will eventually be his undoing. Funny, despairing, moving and absurd, Lima Barreto's masterpiece shows a man and a country caught in the violent clash between illusion and reality, hope and decline, sanity and madness.
