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Molecular and Cellular Biophysics
Molecular and Cellular Biophysics provides advanced undergraduate and graduate students with a foundation in the basic concepts of biophysics. Students who have taken physical chemistry and calculus courses will find this book an accessible and valuable aid in learning how these concepts can be used in biological research. The text provides a rigorous treatment of the fundamental theories in biophysics and illustrates their application with examples. Conformational transitions of proteins are studied first using thermodynamics, and subsequently with kinetics. Allosteric theory is developed as the synthesis of conformational transitions and association reactions. Basic ideas of thermodynamics and kinetics are applied to topics such as protein folding, enzyme catalysis and ion channel permeation. These concepts are then used as the building blocks in a treatment of membrane excitability. Through these examples, students will gain an understanding of the general importance and broad applicability of biophysical principles to biological problems.
A Guide to Online Pharmacy Education
This book describes in detail the various teaching strategies and assessment methods used in pharmacy education. Included in the text is both the advantages and disadvantages of each teaching and assessment method, as well as tips for effective implementation of the strategies. The text covers a plethora of teaching styles, from web based and online learning to lecture and team-based learning, and highlights some of the best practices used worldwide. This book aims to be a valuable single resource for pharmacy educators, students, and researchers. Key features One resource for the pharmacy educators, students, partitioners, researchers, policy makers and other readers with the necessary info...
Vander's Human Physiology
The fundamental purpose of this textbook is to present the principles and facts of human physiology in a format that is suitable for undergraduates regardless of academic background or field of study. The eleventh edition, carries on the tradition of clarity and accuracy, while refining and updating the content to meet the needs of today's instructors and students. The eleventh edition features a streamlined, clinically oriented focus to the study of human body systems. It has also responded to reviewer requests for more clinical applications. Chapter 19 is new and contains three complete case studies. Physiology Inquiries have also been added to many figures throughout the chapters.
Expression and Function of the Histidine-rich Calcium-binding Protein
Although we did not observe any significant defects in calcium handling in the hearts of HRC null mice, expression of the cardiac isoform of triadin (triadin 1) was upregulated in these hearts to compensate for the loss of HRCBP. These observations suggest that HRCBP may indirectly modulate inactivation of the ryanodine receptor (RyR) in response to changes in the luminal calcium concentration. Specifically, HRCBP may antagonize the inhibitory effect of calsequestrin on the ability of triadin to stabilize the open conformation of the RyR as luminal calcium stores are depleted.
