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Fully updated, this revised edition describes the statistical aspects of both the design and analysis of trials, with particular emphasis on the more recent methods of analysis.About 8000 clinical trials are undertaken annually in all areas of medicine, from the treatment of acne to the prevention of cancer. Correct interpretation of the data from such trials depends largely on adequate design and on performing the appropriate statistical analyses. This book provides a useful guide to medical statisticians and others faced with the often difficult problems of designing and analysing clinical trials./a
A pickle tries to escape being eaten by fleeing through the city streets, pursued by a variety of other food items.
Combines classic and cutting-edge scholarship on personal social networks. A must-have resource for both newcomers and seasoned experts.
Motivational concepts pervade the classic theories of delinquency. And yet, there has been little detailed analysis of the relationship between motivation and delinquency. In this 44th volume of the Nebraska Symposium on Motivation, a group of leading scholars in a broad range of fields make up for that scholarly negligence, giving explicit and systematic attention to the subject.øJoan McCord opens the volume by considering fundamental questions about relationships between motivation, explanation, blame, and free will, thereby developing a base from which she poses a theory of motivation for crime. Michael Rutter and colleagues review findings concerning factors ranging from social organiza...
This book unifies and extends latent variable models, including multilevel or generalized linear mixed models, longitudinal or panel models, item response or factor models, latent class or finite mixture models, and structural equation models. Following a gentle introduction to latent variable modeling, the authors clearly explain and contrast a wi
The current economic crisis stems from a deeper crisis of cultural imagination and civilisational ethics: here is the starting point of this collection of essays which draw a new political economy facing the crisis of Western civilization. This bookgathers together a range of audacious and provocative readings of Caritas in Veritate, the first papal encyclical that addresses issues immediately relevant for politic, economic, and social theory. These readings embody the kind of fruitful dialogue Pope Benedict XVI wanted to generate with his radical discourse for an alternative political economy.
Repeated measures data arise when the same characteristic is measured on each case or subject at several times or under several conditions. There is a multitude of techniques available for analysing such data and in the past this has led to some confusion. This book describes the whole spectrum of approaches, beginning with very simple and crude methods, working through intermediate techniques commonly used by consultant statisticians, and concluding with more recent and advanced methods. Those covered include multiple testing, response feature analysis, univariate analysis of variance approaches, multivariate analysis of variance approaches, regression models, two-stage line models, approaches to categorical data and techniques for analysing crossover designs. The theory is illustrated with examples, using real data brought to the authors during their work as statistical consultants.
This book examines childhood personality and behaviour to adulthood from major longitudinal studies in psychopathology.
This book provides an in-depth, multi-dimensional analysis of conversations between autistic adults. The investigation is focussed on intonation style, turn-taking and the use of backchannels, filled pauses and silent pauses. Previous findings on intonation style in the context of autism spectrum disorder (ASD) are contradictory, with claims ranging from characteristically monotonous to characteristically melodic intonation. A novel methodology for quantifying intonation style is used, and it is revealed that autistic speakers tended towards a more melodic intonation style compared to control speakers in the data set under investigation. Research on turn-taking (the organisation of who speak...
The Cultural Construction of Monstrous Children raises important questions at the heart of society and culture, and through an interdisciplinary, trans-cultural analysis presents important findings on socio-cultural representations and embodiments of the child and childhood. At the start of the 21st, new anxieties constellate around the child and childhood, while older concerns have re-emerged, mutated, and grown stronger. But as historical analysis shows, they have been ever-present concerns. This innovative and interdisciplinary collection of essays considers examples of monstrous children since the 16th century to the present, spanning real-life and popular culture, to exhibit the manifestation of the Western cultural anxiety around the problematic, anomalous child as naughty, dangerous, or just plain evil. The book takes an inter- and multidisciplinary approach, drawing upon fields as diverse as sociology, psychology, film, and literature, to study the role of the child and childhood within contemporary Western culture and to see the historic ways in which each discipline intersects and influences the other.