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Ryanodine Receptors
In recent years, the ryanodine receptor has emerged as a new and very promising target for the treatment of several cardiovascular disorders, including cardiac arrhythmias and heart failure. This volume is the most current publication devoted to the major intracellular calcium-release channel, the ryanodine receptor. "In this series of brief but informative chapters, the contributions progress from the basic gene family and primary structure, through its 3D structure so far, to its regulation and physiology." David E. Clapham, MD, PhD Professor of Neurobiology and Pediatrics Harvard Medical School Dr. Xander H.T. Wehrens received his M.D. and Ph.D. degrees from Maastricht University in the N...
Cardiovascular Plaque Rupture
Illustrating the development and determinants of possible plaque rupture, Cardiovascular Plaque Rupture provides an in-depth review of the pathology, etiology, cellular and molecular biology, diagnosis, and treatment of plaque in the cardiovascular system-exploring the roles of physical stress, inflammation, and infectious agents on the growth of c
Integrative Aspects of Calcium Signalling
Here is the first effort in a single volume to cover all of the integrative functions of calcium signalling - how changes in intracellular calcium coordinate a variety of coherent cellular responses. Written by a team of internationally established researchers, Integrative Aspects of Calcium Signalling provides the latest experimental data and concepts, bringing together a detailed analysis of the events, processes, and functions regulated by calcium signalling. A unique resource for professionals and students of physiology, biophysics, neurobiology, biochemistry, and all related fields.
Mitochondria and the Heart
Mitochondria have been pivotal in the development of some of the most important ideas in modern biology. Since the discovery that the organelle has its own DNA and specific mutations were found in association with neuromuscular and cardiovascular diseases and with aging, an extraordi-nary number of publications have followed, and the term mitochondrial medicine was coined. Furthermore, our understanding of the multiple roles that mitochondria play in cardiac cell homeostasis opened the door for intensive experimentation to understand the pathogenesis and to find new treatments for cardiovascular diseases. Besides its role in adenosine triphosphate generation, mitochondria regu-late a complex...
Calcium Signaling
The first edition of James Putney's Calcium Signaling offered readers a comprehensive view of the fascinating diversity of technologies that the new field of calcium signaling employed. And while that work is still regarded as a premier text on the basics of calcium signaling, progress has been so dramatic that an update is now required. In Cal
Roads Not Taken
In Roads Not Taken, Earl J. Wilcox and Jonathan N. Barron bring a new freshness and depth to the study of one of America's greatest poets. While some critics discounted Frost as a poet without technical skill, rhetorical complexity, or intellectual depth, over the past decade scholars have begun to view Robert Frost's work from many new perspectives. Critical hermeneutics, cultural studies, feminism, postmodernism, and textual editing all have had their impact on readings of the poet's life and work. This collection of essays is the first to account for the variety of these new perceptions.
Free Will and Constraint
Free will is an essential problem in human knowledge that investigates the relationships between all creatures, including human beings, with each other, nature, and ecosystem. The immense impacts of free will on science, law, and ethics and, as a result, on everyday life of humans are undeniable. This is the reason behind almost two centuries of intense research by well-known researchers on this historic problem in the Western world. This book, based on a constructive modeling of the problem, provides its solution and analyzes its applications in science, law, and ethics.
Atlas of Practical Applications of Cardiovascular Magnetic Resonance
• Richly illustrated with over 200 illustrations • Contains a Glossary of Terms • Very practical and user-friendly guide
PracticeMind for Everyone
PracticeMind for Everyone is a groundbreaking method book for all musicians that will transform your practice and performance. Hans Jørgen Jensen and Oleksander Mycyk define a mental practice model for piano, percussion, brass, wind, and string players, filling the book with research-backed practice techniques and methods that will dramatically improve your performance results. The ¿rst section delves into the mental, motivational, and psychological aspects of learning. Demystifying the powerful metacognitive learning cycle, the second part of the book focuses on topics such as goal setting and practice planning. The chapters focusing on implementation explore the active part of practicing and the proven techniques you can apply in your daily practice sessions. The ¿nal section of this definitive guide to developing your practice mind encourages active listening, feedback, and evaluation of all steps of your musical journey. PracticeMind for Everyone promotes a practice mindset that inspires greater motivation, effectiveness, and inspiration in all aspects of a musical life on and off the stage.
