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This translation reveals the complex interplay of Spanish history, politics, and European literary influences that characterize the many works of Perez Galdos. An introduction investigates the philosophical influences, especially Krausism, in his realist novels.
Modern drug design and testing involves experimental in vivo and in vitro measurement of the drug candidate's ADMET (adsorption, distribution, metabolism, elimination and toxicity) properties in the early stages of drug discovery. Only a small percentage of the proposed drug candidates receive government approval and reach the market place. Unfavorable pharmacokinetic properties, poor bioavailability and efficacy, low solubility, adverse side effects and toxicity concerns account for many of the drug failures encountered in the pharmaceutical industry. Authors from several countries have contributed chapters detailing regulatory policies, pharmaceutical concerns and clinical practices in their respective countries with the expectation that the open exchange of scientific results and ideas presented in this book will lead to improved pharmaceutical products.
Bly's principal revelation is that Galdós deliberately and consistently used this secondary type to emphasize the significance of the major plot developments and to underline the strengths or weaknesses of principal characters. In filling these roles the eccentric old men develop from comic shallow types into more complex secondary characters, men of insight and wisdom, who occupy a pivotal position in the novels.
Includes names from the States of Alabama, Arkansas, the District of Columbia, Florida, Georgia, Kentucky, Louisiana, Mississippi, North Carolina, Oklahoma, South Carolina, Tennessee, Texas and Virginia, and Puerto Rico and the Virgin Islands.
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Eine Stadt ist wie ein offenes Buch. Als eine zeichenhafte Textur mit eingeschriebenen kulturellen Mustern prägt sie die Lebensformen ihrer Bewohnerinnen und Bewohner und legt bestimmte Arten des Umgangs mit Herausforderungen wie Gentrifizierung oder demografischem Wandel nahe. Auf den Spuren der Mythen Sevillas führt Christiane Schwab durch diese im äußersten Südwesten Europas gelegene Stadt. Die Autorin verknüpft historische Figuren und Ereignisse, ikonische Bauten, urbane Vorstellungswelten und Formen des Freizeit- und Arbeitslebens zu einer facettenreichen Interpretation Sevillas.