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Phospholipases in Physiology and Pathology presents a comprehensive overview on the physiology and pathology of phospholipases. This seven-volume set considers the biochemical and molecular mechanisms of normal and abnormal cell function upon dysregulation of phospholipases in different diseases. Volumes cover signal transduction mechanisms, implications in cancer, infectious diseases, neural diseases, cardiovascular diseases and other diseases, implications in inflammation, apoptosis, gene expression and non-coding RNAs, the role of natural and synthetic compounds, and stem cell therapies, nanotechnology-based therapies, and more. Together, these volumes give researchers critical insight on the mechanistic and therapeutic aspects of phospholipases. - Discusses the biochemical and molecular mechanisms of normal and abnormal cell function in different disease processes - Covers a wide range of basic and translational research appropriate for scientists engaged in studying the regulation of phospholipases from interdisciplinary perspectives - Features state-of-the-art chapter contributions from international leaders in the field
For a few seconds with large machines, scientists and engineers have now created the fusion power of the stars in the laboratory and at the same time find the rich range of complex turbulent electromagnetic waves that transport the plasma confinement systems. The turbulent transport mechanisms created in the laboratory are explained in detail in the second edition of 'Turbulent Transport in Magnetized Plasmas' by Professor Horton.The principles and properties of the major plasma confinement machines are explored with basic physics to the extent currently understood. For the observational laws that are not understood — the empirical confinement laws — offering challenges to the next gener...
This proceedings volume, the sixteenth in a biannual series, presents a snapshot of the state of current research worldwide on Electron Cyclotron Emission (ECE) and Electron Cyclotron Resonance Heating (ECRH) and related technologies. The papers address the physics, both theory and experiment, of ECE and ECRH. The technologies of high power millimeter-wave sources - gyrotrons - and transmission lines and launchers are included. The focus is on physics and technology relevant to the research and development of nuclear fusion.
Bioactive Lipid Mediators in Cardiopulmonary Pharmacology, Volume 97 updates readers on topics surrounding Bioactive lipid mediators. These mediators are involved in a vast array of signaling pathways that regulate both physiological and pathophysiological responses. Chapters in this new release include Cyclooxygenases and Vascular Function, Cyclooxygenases and Platelet Function, Eicosanoids and Cardiomyopathies, Cytochrome P450 Bioactive Lipids in the Heart, Epoxide Hydrolase and Leukotoxin in the Heart and Lung, Role of cytochrome P450-epoxygenase and soluble epoxide hydrolase in the regulation of vascular response, Bioactive Lipids in Hypertension, Cytochrome P450 Metabolites and Angiogen...
This reference book compiles together different animal models in cancer research. It provides knowledge and a better understanding of the advancement of the molecular and cellular mechanisms associated with the progression, formation, and clinical results of various types of cancer from the evidence collected from animal models utilized for cancer research. It discusses animal models for screening anti-cancer drugs and exploration of gene therapy. It presents different methods used to construct cancer animal models and the progress of each animal model in tumor research. The book also highlights the applications of genetic engineering, including CRISP/Cas9, in designing and developing animal models for cancer research. Further, it discusses strategies for modeling animals for investigating growth, metastasis, tumor-associated inflammation and microenvironment, cancer stem cells, tumor heterogeneity, and therapeutic resistance. This book is s a valuable resource for basic and translational cancer researchers, clinicians, and health care.
The purpose of this book is to illustrate the fundamental concepts of complexity and complex behavior and the best methods to characterize this behavior by means of their applications to some current research topics from within the fields of fusion, earth and solar plasmas. In this sense, it is a departure from the many books already available that discuss general features of complexity. The book is divided in two parts. In the first part the most important properties and features of complex systems are introduced, discussed and illustrated. The second part discusses several instances of possible complex phenomena in magnetized plasmas and some of the analysis tools that were introduced in t...
The aim of this book is to introduce the use of NMR and MRI methods for investigating electrochemical storage materials and devices to help both NMR spectroscopists entering the field of batteries and battery specialists seeking diagnostic methods for material and device degradation.