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This book provides detailed information on the surface and surface chemistry of various biointerfaces for the understanding and development of biosensors, biocompatible devices, and drug delivery systems. It highlights the role of interfacial phenomena towards the behaviour of biomolecules on different surfaces and their significance in recent applications. The book also addresses various surface engineering techniques for the modification of biomaterials that are implemented for improving biocompatibility. It provides an updated scientific concept of various interactions of biological systems with surfaces/modified surfaces at the molecular and cellular level. The chapters include various in-vitro, in-vivo, ex-vivo models to illustrate various aspects of Biointerface Engineering. Finally, the book elucidates troubleshooting strategies and future prospects of Biointerface Engineering in Medical Diagnostics and Drug Delivery.
In this day and age, it is unfortunate that the economic prosperity and development leads to disruption of the dynamic balance of the environment. The philosophy of sustainable development has been presented for a long period of time but it has not been able to bring about a substantial change in our society. The transformation of this philosophy into a practical reality seems to be far away – at least in the foreseeable future. In my opinion, the only way I see the revolution taking place is for us to incorporate ‘sustainability’ in our daily living and to keep pushing for a sustainable society. Meanwhile, we also need scientists to work on technologies that would lead us to that goal...
Understanding the molecular mechanisms of cancer is the key for transforming cancer medicine. A substantial proportion of human genes show alternative splicing and mis-regulation of Pre-mRNA splicing is seen in several cancers.This book further investigates these matters. The first few chapters provide an update on the role of genomics in understanding alternative splicing, and targets in cancer pathogenesis. Advances and prospects in applications of nanotechnology for cancer prevention, detection and treatment are a promising field of research. The subsequent chapters provide insights on how nanotechnology-based therapeutics are moving towards revolutionizing cancer and infectious disease treatment by minimizing toxicity and facilitating targeted delivery of drugs. Technical topics discussed in the book include: • Alternative splicing and cancer• Cancer imaging• Nanomaterials in infectious diseases• Nanomedicine in oxidative stress and cancer• Nanoparticle based drug delivery systems
Magnesium (Mg) and its alloys have received widespread acceptance in automobile industries and biomedical applications with substantial recent advancements made in their development, however a significant limitation remains their poor aqueous and galvanic corrosion resistance. This book covers both the fundamentals and recent advancements in two major corrosion protection strategies of magnesium and its alloys, namely, metal-matrix composites and protective coatings. Key features: Covers all aspects of metal-matrix composites and protective coatings for magnesium alloys to improve their corrosion resistance, wear resistance, mechanical properties and biocompatibility Provides the most recent research advancements in the corrosion mitigation strategies of magnesium and its alloys Complete with case studies specific to practical applications, this book serves as a ready reference for graduate students, researchers, engineers and industry professionals in the fields of materials, corrosion science, biofouling and protective coatings.
Magnesium alloys have enormous potential for use in biomedical implants. Magnesium Alloys for Biomedical Applications delves into recent advances and prospects for implementation and provides scientific insights into current issues posed by Mg alloy materials. It provides an overview of research on their mechanical and tribological characteristics, corrosion tendencies, and biological characteristics, with a particular emphasis on biomedical implants. Details the fundamentals of Mg alloys as well as necessary surface modifications of Mg alloys for biomedical use. Discusses emerging Mg alloys and their composites. Covers mechanical, tribological, and chemical properties, as well as fatigue an...
The papers included in this issue of ECS Transactions were originally presented in the symposium "Nanotechnology General Session" held during the 218th meeting of The Electrochemical Society, in Las Vegas, Nevada, from October 10 to 15, 2010.
Research on applications of polymers for biomedical applications has increased dramatically to find improved medical plastics for this rapidly evolving field. This book brings together various aspects of recent research and developments within academia and industry related to polymers for biomedical applications.
Biocatalysis and biomaterials are hot research topics in polymer science, with many new reactions, new biocatalysts, and new biomaterials being discovered and applied. This symposium volume provides up-to-date reviews and articles of these exciting fields.
Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.