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Epigenetics and Complex Traits
  • Language: en
  • Pages: 356

Epigenetics and Complex Traits

This book will provide an overview of basic epigenetic phenomena; interaction between epigenetic and genetic factors; and the influence of epigenetic factors on inheritance. Epigenetic states may contribute to the penetrance of genetic polymorphisms or mutations and thereby modify inheritance patterns. This may result in non‐Mendelian inheritance of genetic traits such as observed in common human disease. The relationship between epigenetics and genetics, however, has not been comprehensively summarized yet. The topic is being more and more appreciated lately due to considerable advances in genomic and epigenomic approaches to study the origins of human disease. The editors will focus not ...

Epigenetics In Human Reproduction And Development
  • Language: en
  • Pages: 304

Epigenetics In Human Reproduction And Development

Epigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from parents to offspring through gametes. Therefore, alterations of epigenetic states would have serious consequences for human development and health. This realization and the advent of new technologies have encouraged the advance of epigenetic studies in recent years. Nonetheless, many aspects of epigenetics, such as regulatory mechanisms and evolutional advantages, remain to be better understood.Written by 26 scientists at the forefront of epigenetics research, this book discusses the different facets of epigenetics: from gametogenesis to child development, as well as from mechanistic studies in animal models to reviews of human clinical data.

Genome Research
  • Language: en
  • Pages: 734

Genome Research

  • Type: Book
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  • Published: 2008
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  • Publisher: Unknown

None

Human Evolutionary Demography
  • Language: en
  • Pages: 572

Human Evolutionary Demography

Human evolutionary demography is an emerging field blending natural science with social science. This edited volume provides a much-needed, interdisciplinary introduction to the field and highlights cutting-edge research for interested readers and researchers in demography, the evolutionary behavioural sciences, biology, and related disciplines. By bridging the boundaries between social and biological sciences, the volume stresses the importance of a unified understanding of both in order to grasp past and current demographic patterns. Demographic traits, and traits related to demographic outcomes, including fertility and mortality rates, marriage, parental care, menopause, and cooperative b...

Methodology for Genetic Studies of Twins and Families
  • Language: en
  • Pages: 503

Methodology for Genetic Studies of Twins and Families

Few would dispute the truth of the statement `People are Different', but there is much controversy over why. This book authoritatively explains the methods used to understand human variation, and extends them far beyond the primary `nature or nurture' question. After chapters on basic statistics, biometrical genetics, matrix algebra and path analysis, there is a state-of-the-art account of how to fit genetic models using the LISREL package. The authors explain not only the assumptions of the twin method, but how to test them. The elementary model is expanded to cover sex limitation, sibling interaction, multivariate and longitudinal data, observer ratings, and twin-family studies. Throughout, the methods are illustrated by applications to diverse areas such as obesity, major depression, alcohol comsumption, delinquency, allergies, and common fears.

A Biographical Dictionary of Women Economists
  • Language: en

A Biographical Dictionary of Women Economists

  • Type: Book
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  • Published: 2008
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  • Publisher: Unknown

Includes over one hundred specially commissioned articles on the lives and writings of women who made significant contributions to economics. It sheds new light on the rich, but too often neglected, heritage of women's analysis of economic issues and participation in the discipline of economics.

Biosocial Worlds
  • Language: en
  • Pages: 230

Biosocial Worlds

  • Type: Book
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  • Published: 2020-09-29
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  • Publisher: UCL Press

Biosocial Worlds presents state-of-the-art contributions to anthropological reflections on the porous boundaries between human and non-human life – biosocial worlds. Based on changing understandings of biology and the social, it explores what it means to be human in these worlds. Growing separation of scientific disciplines for more than a century has maintained a separation of the ‘natural’ and the ‘social’ that has created a space for projections between the two. Such projections carry a directional causality and so constitute powerful means to establish discursive authority. While arguing against the separation of the biological and the social in the study of human and non-human...

CIHR, the Power of Volunteers
  • Language: en
  • Pages: 72

CIHR, the Power of Volunteers

  • Type: Book
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  • Published: 2006
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  • Publisher: Unknown

None

Apomixis in Angiosperms
  • Language: en
  • Pages: 160

Apomixis in Angiosperms

  • Type: Book
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  • Published: 1992-11-18
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  • Publisher: CRC Press

Apomixis in Angiosperms: Nucellar and Integumentary Embryony is based on original cytoembryological data and critically reviewed literature on more than 250 species from 57 families of angiosperms. The book covers the complete process of nucellar and integumentary embryo formation and viable seed development within species, families, and among angiosperms in general. Many species (some of which are economically important) characterized by adventive embryony are listed. The book also provides an original simple classification of apomixis and offers a new approach to differentiating embryological structures in cases of apomixis and amphimixis. Apomixis in Angiosperms: Nucellar and Integumentary Embryony will be a useful reference for embryologists, botanists, cytologists, geneticists, and plant breeders. It will also benefit any researcher interested in studying somatic embryo formation in tissue culture.

Gene Prediction
  • Language: en
  • Pages: 284

Gene Prediction

  • Type: Book
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  • Published: 2019-05-19
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  • Publisher: Humana Press

This volume introduces software used for gene prediction with focus on eukaryotic genomes. The chapters in this book describe software and web server usage as applied in common use-cases, and explain ways to simplify re-annotation of long available genome assemblies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary computational requirements, step-by-step, readily reproducible computational protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Gene Prediction: Methods and Protocols is a valuable resource for researchers and research groups working on the assembly and annotation of single species or small groups of species. Chapter 3 is available open access under a CC BY 4.0 license via link.springer.com.