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The Phylogenetic Handbook
A broad, hands on guide with detailed explanations of current methodology, relevant exercises and popular software tools.
The Phylogenetic Handbook
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Combination Therapy of AIDS
An extensive assessment of combination therapy of AIDS. Main focus is put on the Highly Active Antiretroviral Therapy (HAART) but other therapies like salvage therapy are also discussed. The chapters cover efficacy, treatment, causes of treatment failure, clinical care, guidelines, pharmacology. The volume closes with an outlook on future perspectives.
The Phylogenetic Handbook
The Phylogenetic Handbook is a broad, hands on guide to theory and practice of nucleotide and protein phylogenetic analysis. This second edition includes six new chapters, covering topics such as Bayesian inference, tree topology testing and the impact of recombination on phylogenies, as well as a detailed section on molecular adaptation. The book has a stronger focus on hypothesis testing than the previous edition, with more extensive discussions on recombination analysis, detecting molecular adaptation and genealogy-based population genetics. Many chapters include elaborate practical sections, which have been updated to introduce the reader to the most recent versions of sequence analysis and phylogeny software, including BLAST, FastA, Clustal, T-coffee, Muscle, DAMBE, Tree-puzzle, Phylip, MEGA, PAUP*, IQPNNI, CONSEL, ModelTest, Prottest, PAML, HYPHY, MrBayes, BEAST, LAMARC, SplitsTree, and RDP. Many analysis tools are described by their original authors, resulting in clear explanations that constitute an ideal teaching guide for advanced-level undergraduate and graduate students.
Viral Genome Replication
This book provides the first comprehensive review of viral genome replication strategies, emphasizing not only pathways and regulation but also the structure-function, mechanism, and inhibition of proteins and enzymes required for this process.
The Routledge Handbook of Historical Linguistics
The Routledge Handbook of Historical Linguistics provides a survey of the field covering the methods which underpin current work; models of language change; and the importance of historical linguistics for other subfields of linguistics and other disciplines. Divided into five sections, the volume encompass a wide range of approaches and addresses issues in the following areas: historical perspectives methods and models language change interfaces regional summaries Each of the thirty-two chapters is written by a specialist in the field and provides: a introduction to the subject; an analysis of the relationship between the diachronic and synchronic study of the topic; an overview of the main current and critical trends; and examples from primary data. The Routledge Handbook of Historical Linguistics is essential reading for researchers and postgraduate students working in this area. Chapter 28 of this book is freely available as a downloadable Open Access PDF under a Creative Commons Attribution-Non Commercial-No Derivatives 3.0 license. https://www.routledgehandbooks.com/doi/10.4324/9781315794013.ch28
The Routledge Handbook of Translation, Interpreting and Crisis
This handbook offers a broad-ranging overview of the study of translating and interpreting in conflict and crisis settings and takes the field in new directions. Covering a wide selection of multimodal contexts that build on the fundamentals of translation, interpreting, and their in-between hybrid forms of mediation, the handbook is divided into four parts. The opening part covers perspectives on policy and practices, whether contemporary or historical, and cases truly span the globe, from Peru and Brazil, over Belgium and Sierra Leone, to Australia, Japan, and Hong Kong. International developments require profound considerations about the professionalisation of access to language in times ...
Handbook of Stemmatology
Stemmatology studies aspects of textual criticism that use genealogical methods to analyse a set of copies of a text whose autograph has been lost. This handbook is the first to cover the entire field, encompassing both theoretical and practical aspects of traditional as well as modern digital methods and their history. As an art (ars), stemmatology’s main goal is editing and thus presenting to the reader a historical text in the most satisfactory way. As a more abstract discipline (scientia), it is interested in the general principles of how texts change in the process of being copied. Thirty eight experts from all of the fields involved have joined forces to write this handbook, whose ei...
