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Theory of Statistical Inference
The purpose of applying mathematical theory to the theory of statistical inference is to make it simpler and more elegant. Theory of Statistical Inference is concerned with the development of a type of optimization theory which can be used to inform the choice of statistical methodology.
Theory of Statistical Inference
Theory of Statistical Inference is designed as a reference on statistical inference for researchers and students at the graduate or advanced undergraduate level. It presents a unified treatment of the foundational ideas of modern statistical inference, and would be suitable for a core course in a graduate program in statistics or biostatistics. The emphasis is on the application of mathematical theory to the problem of inference, leading to an optimization theory allowing the choice of those statistical methods yielding the most efficient use of data. The book shows how a small number of key concepts, such as sufficiency, invariance, stochastic ordering, decision theory and vector space alge...
Statistical Modeling for Biological Systems
This book commemorates the scientific contributions of distinguished statistician, Andrei Yakovlev. It reflects upon Dr. Yakovlev’s many research interests including stochastic modeling and the analysis of micro-array data, and throughout the book it emphasizes applications of the theory in biology, medicine and public health. The contributions to this volume are divided into two parts. Part A consists of original research articles, which can be roughly grouped into four thematic areas: (i) branching processes, especially as models for cell kinetics, (ii) multiple testing issues as they arise in the analysis of biologic data, (iii) applications of mathematical models and of new inferential...
Statistical Theory
Designed for a one-semester advanced undergraduate or graduate statistical theory course, Statistical Theory: A Concise Introduction, Second Edition clearly explains the underlying ideas, mathematics, and principles of major statistical concepts, including parameter estimation, confidence intervals, hypothesis testing, asymptotic analysis, Bayesian inference, linear models, nonparametric statistics, and elements of decision theory. It introduces these topics on a clear intuitive level using illustrative examples in addition to the formal definitions, theorems, and proofs. Based on the authors’ lecture notes, the book is self-contained, which maintains a proper balance between the clarity a...
Design and Analysis of Experiments and Observational Studies using R
Introduction to Design and Analysis of Scientific Studies exposes undergraduate and graduate students to the foundations of classical experimental design and observational studies through a modern framework - The Rubin Causal Model. A causal inference framework is important in design, data collection and analysis since it provides a framework for investigators to readily evaluate study limitations and draw appropriate conclusions. R is used to implement designs and analyse the data collected. Features: Classical experimental design with an emphasis on computation using tidyverse packages in R. Applications of experimental design to clinical trials, A/B testing, and other modern examples. Discussion of the link between classical experimental design and causal inference. The role of randomization in experimental design and sampling in the big data era. Exercises with solutions. Instructor slides in RMarkdown, a new R package will be developed to be used with book, and a bookdown version of the book will be freely available. The proposed book will emphasize ethics, communication and decision making as part of design, data analysis, and statistical thinking.
A Course in the Large Sample Theory of Statistical Inference
Provides accessible introduction to large sample theory with moving alternatives Elucidates mathematical concepts using simple practical examples Includes problem sets and solutions for each chapter Uses the moving alternative formulation developed by LeCam but requires a minimum of mathematical prerequisites
Fundamentals of Mathematical Statistics
Fundamentals of Mathematical Statistics is meant for a standard one-semester advanced undergraduate or graduate-level course in Mathematical Statistics. It covers all the key topics—statistical models, linear normal models, exponential families, estimation, asymptotics of maximum likelihood, significance testing, and models for tables of counts. It assumes a good background in mathematical analysis, linear algebra, and probability but includes an appendix with basic results from these areas. Throughout the text, there are numerous examples and graduated exercises that illustrate the topics covered, rendering the book suitable for teaching or self-study. Features A concise yet rigorous introduction to a one-semester course in Mathematical Statistics Covers all the key topics Assumes a solid background in Mathematics and Probability Numerous examples illustrate the topics Many exercises enhance understanding of the material and enable course use This textbook will be a perfect fit for an advanced course in Mathematical Statistics or Statistical Theory. The concise and lucid approach means it could also serve as a good alternative, or supplement, to existing texts.
Applied Categorical and Count Data Analysis
Developed from the authors’ graduate-level biostatistics course, Applied Categorical and Count Data Analysis, Second Edition explains how to perform the statistical analysis of discrete data, including categorical and count outcomes. The authors have been teaching categorical data analysis courses at the University of Rochester and Tulane University for more than a decade. This book embodies their decade-long experience and insight in teaching and applying statistical models for categorical and count data. The authors describe the basic ideas underlying each concept, model, and approach to give readers a good grasp of the fundamentals of the methodology without relying on rigorous mathemat...
Time Series for Data Science
Data Science students and practitioners want to find a forecast that “works” and don’t want to be constrained to a single forecasting strategy, Time Series for Data Science: Analysis and Forecasting discusses techniques of ensemble modelling for combining information from several strategies. Covering time series regression models, exponential smoothing, Holt-Winters forecasting, and Neural Networks. It places a particular emphasis on classical ARMA and ARIMA models that is often lacking from other textbooks on the subject. This book is an accessible guide that doesn’t require a background in calculus to be engaging but does not shy away from deeper explanations of the techniques disc...
Quantitative Assessment and Validation of Network Inference Methods in Bioinformatics
Scientists today have access to an unprecedented arsenal of high-tech tools that can be used to thoroughly characterize biological systems of interest. High-throughput “omics” technologies enable to generate enormous quantities of data at the DNA, RNA, epigenetic and proteomic levels. One of the major challenges of the post-genomic era is to extract functional information by integrating such heterogeneous high-throughput genomic data. This is not a trivial task as we are increasingly coming to understand that it is not individual genes, but rather biological pathways and networks that drive an organism’s response to environmental factors and the development of its particular phenotype....
