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Presents the most effective catalytic reactions in use today, with a special focus on process intensification, sustainability, waste reduction, and innovative methods This book demonstrates the importance of efficient catalytic transformations for producing pharmaceutically active molecules. It presents the key catalytic reactions and the most efficient catalytic processes, including their significant advantages over compared previous methods. It also places a strong emphasis on asymmetric catalytic reactions, process intensification (PI), sustainability and waste mitigation, continuous manufacturing processes as enshrined by continuous flow catalysis, and supported catalysis. Active Pharmac...
This "hands-on" approach to the topic of arylation consolidates the body of key research over the last ten years (and up to around 2014) on various catalytic methods which involve an arylation process. Clearly structured, the chapters in this one-stop resource are arranged according to the reaction type, and focus on novel, efficient and sustainable processes, rather than the well-known and established cross-coupling methods. The entire contents are written by two authors with academic and industrial expertise to ensure consistent coverage of the latest developments in the field, as well as industrial applications, such as C-H activation, iron and gold-catalyzed coupling reactions, cycloadditions or novel methodologies using arylboron reagents. A cross-section of relevant tried-and-tested experimental protocols is included at the end of each chapter for putting into immediate practice, along with patent literature. Due to its emphasis on efficient, "green" methods and industrial applications of the products concerned, this interdisciplinary text will be essential reading for synthetic chemists in both academia and industry, especially in medicinal and process chemistry.
At a time of grave ethical failure in global security affairs, this is the first book to bring together emerging theoretical debates on ethics and ethical reasoning within security studies. In this volume, working from a diverse range of perspectives—poststructuralism, liberalism, feminism, just war, securitization, and critical theory—leading scholars in the field of security studies consider the potential for ethical visions of security, and lay the ground for a new field: "ethical security studies". These ethical ‘visions’ of security engage directly with the meaning and value of security and security practice, and consider four key questions: • Who, or what, should be secured? ...
The Routledge Reviewer’s Guide to Mixed Methods Analysis is a groundbreaking edited book – the first devoted solely to mixed methods research analyses, or mixed analyses. Each of the 30 seminal chapters, authored by internationally renowned scholars, provides a simple and practical introduction to a method of mixed analysis. Each chapter demonstrates "how to conduct the analysis" in easy-to-understand language. Many of the chapters present new topics that have never been written before, and all chapters offer cutting-edge approaches to analysis. The book contains the following four sections: Part I Quantitative Approaches to Qualitative Data (e.g., factor analysis of text, multidimension...
Invaluable to students and those approaching the subject for the first time, An Introduction to International Relations, Second Edition provides a comprehensive and stimulating introduction to international relations, its traditions and its changing nature in an era of globalisation. Thoroughly revised and updated, it features chapters written by a range of experts from around the world. It presents a global perspective on the theories, history, developments and debates that shape this dynamic discipline and contemporary world politics. Now in full-colour and accompanied by a password-protected companion website featuring additional chapters and case studies, this is the indispensable guide to the study of international relations.
This innovative volume gathers some of the world’s best scholars to analyse the world’s collective international efforts to address globalised threats through global security governance. Addressing global and planetary forms of insecurity that include nuclear weapons, conventional arms, gender violence, climate change, disease, bio weapons, cyber-conflict, children in conflict, crimes against humanity, and refugees, this timely book critiques how they are addressed by global institutions and regimes, and advocates important conceptual, institutional, and policy reforms. This is an invaluable resource for students, scholars and policymakers in international health, security and development.
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