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The Jurist ..
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Exploring the State of the Science in the Field of Regenerative Medicine
Regenerative medicine holds the potential to create living, functional cells and tissues that can be used to repair or replace those that have suffered potentially irreparable damage due to disease, age, traumatic injury, or genetic and congenital defects. The field of regenerative medicine is broad and includes research and development components of gene and cell therapies, tissue engineering, and non-biologic constructs. Although regenerative medicine has the potential to improve health and deliver economic benefits, this relatively new field faces challenges to developing policies and procedures to support the development of novel therapies are both safe and effective. In October 2016, the National Academies of Sciences, Engineering, and Medicine hosted a public workshop with the goal of developing a broad understanding of the opportunities and challenges associated with regenerative medicine cellular therapies and related technologies. Participants explored the state of the science of cell-based regenerative therapies within the larger context of patient care and policy. This publication summarizes the presentations and discussions from the workshop.
Orthobiologics
Developed in partnership with the American Academy of Orthopaedic Surgeons (AAOS) and edited by internationally renowned experts Drs. Scott P. Bruder and Roy K. Aaron, Orthobiologics: Scientific and Clinical Solutions for Orthopaedic Surgeons provides authoritative, comprehensive coverage of this fast-growing field. This one-stop reference is an ideal resource, covering technology and basic science through specific clinical applications.
Mudlarks
Mudlarks is a tragic, beautifully realised play about three young men trapped at the wrong end of the river. On the muddy banks of the Thames, downstream from the bright lights of London, three boys hide from the police after a night of recklessness. Over the course of the freezing night their fears, secrets and dreams emerge, collide and combust revealing the desperate frustration of lives barely led but already ravaged. As morning dawns, their options diminish and just two questions remain: do they have the power to determine their own fates, or are they destined to sink into the mud? Mudlarks heralds the arrival of an urgent new voice in British theatre. Essex-born Vickie Donoghue'spowerful debut exposes the culture she grew up with and sees on a daily basis. With brutal honesty she explores teenagers' impulse to dream, and its futility in a reality that has no space for dreamers.
Proteoglycans
This book provides a comprehensive, up-to-date review of the structure, biology, and molecular interactions of proteoglycans, consolidating into a single source research using molecular, cellular, and animal systems. Of particular note is an in-depth look at the role of heparan sulfate in modulating growth factors and morphogens.
