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Order and Connexion
The papers in this volume are by past holders of the Cambridge post of Munby Fellow, founded in 1977 in memory of the bibliographical scholar, Alan Munby. Covering a diverse range of topics, they illustrate the variety of ways in which bibliographical evidence is used to determine significant features of both and printed books.
Binding, Transport and Storage of Metal Ions in Biological Cells
A comprehensive overview of the molecular nature of metal ions in nutrition, toxicology and pharmacology.
The New Circlemakers
What is the mystery of the crop circles? Are they manmade or supernatural? Today the majestic crop formations grace the very same pastures of southern England that in the past were the haunts of fairies, hobgoblins, and mysterious lights. Here, too, are some of Britain's most spectacular prehistoric landscapes: Stonehenge, Avebury, and Silbury Hill all act as ominous backdrops to the crop circle phenomenon. Did our ancestors know something about this beguiling, enchanting landscape that we are only now waking up to for the first time? Is there a higher intelligence responsible for such creations, and if so, who are they and what are they trying to tell us? Bizarrely, the answer might lie not here on earth, but 37,000 light years away in the constellation of Cygnus, the Northern Cross, where lurks a star perhaps responsible not only for the foundation of the world's earliest stone monuments but for the emergence of humanity itself.
Functional Nanometer-Sized Clusters of Transition Metals
This book highlights recent progress and challenges in size-controlled synthesis, size-dependent properties, characterization and applications of metal nanoclusters.
Nanoscopic Materials
In recent years there have been great advances in the development of new nanomaterials. To facilitate the progress of new materials it is essential to understand the underlying principles at the nanoscale. Nanoscopic Materials provides an accessible overview of the physico-chemical and physical principles of nanomaterials including electronic structure, magnetic properties, thermodynamics of size dependence and phase transitions and dynamics of clusters and two-dimensional systems. This new edition has been fully revised and updated to reflect recent developments in new nanomaterials including graphene and core–shell structures, properties of nano-structured and intelligent surfaces as well as applications in catalysis and energy. Additional chapters cover the development of nucleation and crystal shape engineering; self-assembly and biomimetics for fabricating nanostructures. With helpful illustrations and summaries of key points in every chapter, this advanced textbook is ideal for graduate students of chemistry and materials science and researchers new to the field of nanoscience and nanotechnology.
The Biological Chemistry of Nickel
Metal ions play key roles in biology. Many are essential for catalysis, for electron transfer and for the fixation, sensing, and metabolism of gases. Others compete with those essential metal ions or have toxic or pharmacological effects. This book is structured around the periodic table and focuses on the control of metal ions in cells. It addresses the molecular aspects of binding, transport and storage that ensure balanced levels of the essential elements. Organisms have also developed mechanisms to deal with the non-essential metal ions. However, through new uses and manufacturing processes, organisms are increasingly exposed to changing levels of both essential and non-essential ions in...
Gasotransmitters
Gasotransmitters are gas molecules produced endogenously in prokaryotic and eukaryotic cells for signalling purposes. This book provides, for the first time, a comprehensive description and systematic look at all gasotransmitters, established or proposed, since their detection in 2002. The content and scope covers the production, metabolism, and signalling roles of gasotransmitters. Conceptual advances, scientific discoveries and newly developed techniques described in this book influence our understanding of fundamental molecular and cellular events in biology and medicine. This book serves as the state-of-the-art book for undergraduate and graduate students as well as post-doctoral fellows in biomedical disciplines and toxicologists studying the toxic mechanisms of gasotransmitters in the environment. It will also be welcomed by researchers in university and research institutes, government agencies, pharmaceutical and medical instrument industry, and clinical practice.
Metal Chelation in Medicine
Metal chelators are emerging as versatile tool with many medical applications. Their versatility allows them to be used in chelation therapy for treating diseases caused by toxic and heavy metal poisoning, chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body removing them from intracellular or extracellular spaces. In addition, metal chelators can also be applied as contrast agents in MRI scanning. Metal Chelation in Medicine provides a clear and timely perspective on the role of chelating agents in the management of metal intoxications and storage diseases. Written by leaders in the field of chelators, this publicatio...
Metalloenzymes in Denitrification
The reduction of nitrate to nitrogen by metalloenzymes is a vital step in the nitrogen cycle. The importance of this pathway has inspired efforts to understand in greater depth the mechanisms involved. This book presents and discusses the latest information on multiple aspects of denitrification. Written by recognized specialists in the field, this book describes the bioinorganic aspects and the key enzymes involved in denitrification, including their structure, function and mechanisms. Active site modelling, novel methodologies for monitoring denitrification in vivo and biotechnological methods for water treatment are discussed. The book also focusses on the environmental implications of denitrification, such nitrate accumulation and the release of nitrous oxide into the atmosphere from excessive fertiliser use. An important topic in many biological, environmental and agricultural contexts, this book will aid teaching and help bioinorganic chemists and biotechnologists gain an up-to-date picture of the science behind the denitrification process.
