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Anticonvulsants
Medicinal Chemistry: A Series of Monographs, Volume 15: Anticonvulsants discusses the laboratory evaluation, drug disposition, clinical evaluation, and synthesis and design of anticonvulsant drugs. This book is organized into eight chapters. Chapters 1 and 2 provide an overview and neuropharmacological background of anticonvulsants. The laboratory evaluation of compounds is described in Chapter 3, while drug disposition is treated in Chapter 4. The chemistry and biological activities of the various classes of anticonvulsant compounds, such as cyclic ureides, benzopyrans, heterocyclic drugs, and noncyclic anticonvulsants are presented in Chapters 5 to 8. This volume is written specifically for medicinal chemists, biochemists, neurologists, and pharmacologists.
New Anticonvulsants
New Anticonvulsants Advances in the Treatment of Epilepsy Edited by M.R. Trimble Department of Neurology, Institute of Neurology, Queen Square, London, UK A variety of new drugs are now available for the treatment of epilepsy representing the first introduction of new anticonvulsants for nearly a decade. This concise book refreshes the reader’s knowledge of some fundamental principles of anticonvulsant actions and reviews in detail the results of clinical research and experience with a range of the new drugs. The chapters are written by internationally recognized experts with direct experience of the anticonvulsant under review. The emphasis is very much on practical clinical management making this book an important and valuable resource for all clinicians that treat epilepsy.
New Antiepileptic Drugs
The pharmacological fight against epilepsy began many centuries ago when Hippocrates discovered that the cause of epilepsy is natural, as opposed to supernatural and, as a consequence, must be treated with a natural remedy. Even though science has significantly progressed since that era, the challenge to find remedies for epilepsy is ever present. The aim of this particular volume is to offer an up-to-date review of the most recent advances in antiepileptic drug development, considered from various viewpoints: (i) general, by taking into account the size of refractory epilepsy and its related problems; (ii) experimental, by exploring the mechanisms of epileptogenesis and the possiblility of influencing it through drugs, and (iii) clinical, by describing the results obtained with compounds currently at an advanced stage of testing.
Psychopharmacology of Anticonvulsants
"Clear, concise, and sophisticated. ... Topics are appropriately covered in great detail and provide a keen insight into several highly topical issues in epileptology." --Clinical Pharmacy (British Association for Psychopharmacology Monographs)
Antiepileptic Drugs
With contributions by numerous experts
Antiepileptic Drugs
Epileptic disorders need treatment for many years or even for life, and this makes a thorough understanding of the pharmacokinetics and possible hazards and side effects of the drugs used in treatment mandatory. During recent decades our knowledge in this field has considerably increased, not least as a result of the development of specific and sensitive methods for the determination of anti epileptic agents in biological material. The clinical pharmacology of this group of drugs has been studied extensively and can today be regarded as well established. This does not necessarily mean that drug treatment of epilepsy is without problems. For example, it has recently been shown that one of the...
